MediWound Ltd. (NASDAQ:MDWD) Poised For Near-Term Repricing As Clinical And Manufacturing Catalysts Arrive

MediWound heads into the coming weeks with a catalyst cadence — advancing EscharEx trials while scaling NexoBrid manufacturing — that could force a near-term market revaluation. Operational cash and program milestones shape the immediate risk/reward profile.

Recent News

On August 14, 2025 the company released second-quarter 2025 results and said U.S. NexoBrid adoption continues to grow, manufacturing commissioning remains on track for full operational readiness by year-end 2025, and the DoD provided an additional $3.6 million for a room-temperature stable NexoBrid formulation. On August 13, 2025 a Phase II post‑hoc clinical analysis for EscharEx appeared in a peer‑reviewed journal showing favorable debridement and wound‑healing signals versus collagenase in venous leg ulcers; the VALUE Phase III enrollment remains ongoing with interim assessment planned for mid‑2026.

Technical Analysis

Directional indicators show competing pressure: ADX at 28.1 signals a strong trending environment while the positive directional index recently dip‑and‑reversed (DI+ at 19.93) — a bullish development — even as the negative directional index also dip‑and‑reversed (DI‑ at 21.09), indicating prevailing negative directional pressure currently exceeds positive directional pressure. That combination implies trend strength with downside bias unless DI+ sustains its advance.

MACD reads negative at -0.29 and the MACD trend shows a peak‑and‑reversal, a bearish momentum characteristic, but MACD sits above its signal line (-0.29 vs. -0.39), a short‑term bullish cross. The result: short‑term momentum has shifted upward while underlying momentum recently rolled over, producing a conflicted momentum picture.

MRO registers 1.94 with a dip‑and‑reversal; that positive MRO places price above the model target and implies potential downward pressure until mean reversion occurs. RSI at 41.59 with a dip‑and‑reversal shows a recent uptick from lower levels but remains below the midpoint, capping broad bullish conviction.

Price action sits above the 20‑day average ($17.11) and near the 12‑day EMA ($17.26) yet below the 50‑day ($18.42) and 200‑day ($18.32) averages; price recently crossed above the -1x standard‑deviation Bollinger band, consistent with a short‑term mean reversion move toward the 20‑day mean. Volume today (51,549) trails the 10‑day average (200,226), signaling limited participation behind the recent move and raising the risk of follow‑through failure without higher volume support.

 


Fundamental Analysis

Revenue and growth: total revenue stands at $5,708,000 and YoY revenue growth reads 21.23%. Quarterly revenue change shows a sequential decline of approximately -2.37% QoQ. Gross margin at 23.51% provides a constructive base for product economics, and YoY gross margin expanded materially versus prior periods.

Profitability and earnings: operating income equals -$5,716,000, producing an operating (EBIT) margin of -100.14%. The company reported EPS of -$1.23 versus an estimate of -$0.57, creating an EPS surprise of -115.79% and an EPS shortfall of -$0.66 per share. Worsened operating leverage drives the large negative margins despite revenue growth.

Cash, liquidity and leverage: cash and short‑term investments total $32,436,000 against total debt of $8,070,000. Current ratio sits at 1.48 and quick ratio at 1.35; cash ratio equals 1.12, indicating cash coverage of short‑term obligations. Debt to equity equals 40.11% while interest coverage remains negative, reflecting ongoing operating losses. Free cash flow stands at -$6,805,000 and free cash flow yield at -3.37%, weaker than the industry peer mean, reflecting elevated cash burn during clinical investment and manufacturing scale‑up.

Working capital and capital efficiency: days inventory outstanding (105.28 days) and days payables outstanding (154.19 days) combine into a cash conversion cycle of 46.81 days. Asset turnover runs low at 0.08393, showing limited revenue per dollar of assets but improving sequentially.

Peer context where available: the EBIT margin of -100.14% sits below the industry peer mean of about -0.75% and below the industry peer median of 23.76% (industry peer range provided); price‑to‑book equals 10.02x versus an industry peer mean near 5.28x; debt‑to‑equity at ~40.11% sits above the industry peer mean of ~25.57%. These comparisons show MediWound carries deeper negative margins while trading at a premium multiple to book and holding higher leverage versus the industry peer mean and median where supplied.

Valuation: WMDST values the stock as under‑valued. That determination reflects a combination of program‑driven optionality (EscharEx VALUE enrollment and registrational pathway), expanding commercial traction for NexoBrid, and a cash balance sizable enough to fund near‑term operations through planned manufacturing commissioning, balanced against substantial negative margins and cash burn.

MOST-RECENT QUARTERLY REPORT
REPORT PERIOD ENDING: 2025-06-30
REPORT DATE: 2025-08-14
NEXT REPORT DATE: 2025-11-19
CASH FLOW  Begin Period Cash Flow 1.4 M
 Operating Cash Flow -5.76 M
 Capital Expenditures -1.05 M
 Change In Working Capital -1.10 M
 Dividends Paid
 Cash Flow Delta -300.00 K
 End Period Cash Flow 1.1 M
 
INCOME STATEMENT REVENUE
 Total Revenue 5.7 M
 Forward Revenue 646.7 K
COSTS
 Cost Of Revenue 4.4 M
 Depreciation 394.0 K
 Depreciation and Amortization 394.0 K
 Research and Development 3.5 M
 Total Operating Expenses 11.4 M
PROFITABILITY
 Gross Profit 1.3 M
 EBITDA -5.32 M
 EBIT -5.72 M
 Operating Income -5.72 M
 Interest Income
 Interest Expense 7.6 M
 Net Interest Income -7.56 M
 Income Before Tax -13.28 M
 Tax Provision 38.0 K
 Tax Rate 21.0 %
 Net Income -13.32 M
 Net Income From Continuing Operations -13.32 M
EARNINGS
 EPS Estimate -0.57
 EPS Actual -1.23
 EPS Difference -0.66
 EPS Surprise -115.789 %
 Forward EPS -0.56
 
BALANCE SHEET ASSETS
 Total Assets 67.0 M
 Intangible Assets 66.0 K
 Net Tangible Assets 20.1 M
 Total Current Assets 43.1 M
 Cash and Short-Term Investments 32.4 M
 Cash
 Net Receivables 6.8 M
 Inventory 3.8 M
 Long-Term Investments
LIABILITIES
 Accounts Payable 5.9 M
 Short-Term Debt
 Total Current Liabilities 29.1 M
 Net Debt
 Total Debt 8.1 M
 Total Liabilities 46.9 M
EQUITY
 Total Equity 20.1 M
 Retained Earnings
VALUATION & PER-SHARE METRICS EQUITY & PER-SHARE METRICS
 Book Value Per-Share 1.86
 Shares Outstanding 10.876 M
 Revenue Per-Share 0.53
VALUATION
 Market Capitalization 201.7 M
 Enterprise Value 177.3 M
 Enterprise Multiple -33.315
Enterprise Multiple QoQ 0.745 %
Enterprise Multiple YoY -1.828 %
Enterprise Multiple IPRWA high: 47.216
median: 14.143
mean: 5.445
MDWD: -33.315
low: -68.907
 EV/R 31.062
CAPITAL STRUCTURE
 Asset To Equity 3.33
 Asset To Liability 1.429
 Debt To Capital 0.286
 Debt To Assets 0.12
Debt To Assets QoQ 29.405 %
Debt To Assets YoY 8.592 %
Debt To Assets IPRWA high: 0.995
mean: 0.195
MDWD: 0.12
median: 0.062
low: 0.0
 Debt To Equity 0.401
Debt To Equity QoQ 95.263 %
Debt To Equity YoY 12.785 %
Debt To Equity IPRWA high: 1.577
MDWD: 0.401
mean: 0.256
median: 0.059
low: -1.039
PRICE-BASED VALUATION
 Price To Book (P/B) 10.024
Price To Book QoQ 62.596 %
Price To Book YoY 9.946 %
Price To Book IPRWA high: 16.592
MDWD: 10.024
median: 6.295
mean: 5.28
low: -9.599
 Price To Earnings (P/E) -18.364
Price To Earnings QoQ -92.793 %
Price To Earnings YoY -28.817 %
Price To Earnings IPRWA high: 44.732
mean: -11.163
MDWD: -18.364
median: -19.0
low: -73.374
 PE/G Ratio -0.013
 Price To Sales (P/S) 35.331
Price To Sales QoQ -27.519 %
Price To Sales YoY 9.802 %
Price To Sales IPRWA high: 517.227
mean: 56.266
MDWD: 35.331
median: 19.711
low: 0.25
FORWARD MULTIPLES
Forward P/E -34.744
Forward PE/G -0.025
Forward P/S 313.783
EFFICIENCY OPERATIONAL
 Operating Leverage 0.212
ASSET & SALES
 Asset Turnover Ratio 0.084
Asset Turnover Ratio QoQ 51.225 %
Asset Turnover Ratio YoY -0.804 %
Asset Turnover Ratio IPRWA high: 0.388
mean: 0.115
median: 0.113
MDWD: 0.084
low: -0.001
 Receivables Turnover 0.953
Receivables Turnover Ratio QoQ 20.222 %
Receivables Turnover Ratio YoY -3.932 %
Receivables Turnover Ratio IPRWA high: 6.517
median: 1.422
mean: 1.408
MDWD: 0.953
low: 0.012
 Inventory Turnover 1.176
Inventory Turnover Ratio QoQ 14.672 %
Inventory Turnover Ratio YoY -16.909 %
Inventory Turnover Ratio IPRWA high: 2.946
MDWD: 1.176
mean: 0.605
median: 0.415
low: 0.006
 Days Sales Outstanding (DSO) 95.726
CASH CYCLE
 Cash Conversion Cycle Days (CCC) 46.811
Cash Conversion Cycle Days QoQ -47.439 %
Cash Conversion Cycle Days YoY -46.219 %
Cash Conversion Cycle Days IPRWA high: 1258.184
median: 205.05
mean: 202.907
MDWD: 46.811
low: -1350.846
CAPITAL DEPLOYMENT
 Cash Conversion Ratio 0.407
 CapEx To Revenue -0.184
 CapEx To Depreciation -2.662
 
CAPITAL, LIQUIDITY & COVERAGE CAPITAL STRUCTURE
 Total Capital 20.1 M
 Net Invested Capital
 Invested Capital -24.37 M
 Net Tangible Assets 20.1 M
 Net Working Capital 14.0 M
LIQUIDITY
 Cash Ratio 1.116
 Current Ratio 1.482
Current Ratio QoQ -31.164 %
Current Ratio YoY -10.202 %
Current Ratio IPRWA high: 24.698
mean: 3.941
median: 2.52
MDWD: 1.482
low: 0.021
 Quick Ratio 1.35
Quick Ratio QoQ -32.138 %
Quick Ratio YoY -10.515 %
Quick Ratio IPRWA high: 14.041
mean: 2.972
median: 2.158
MDWD: 1.35
low: 0.021
COVERAGE & LEVERAGE
 Debt To EBITDA -1.516
 Cost Of Debt 82.456 %
 Interest Coverage Ratio -0.756
Interest Coverage Ratio QoQ -65.217 %
Interest Coverage Ratio YoY -59.469 %
Interest Coverage Ratio IPRWA high: 940.414
mean: 45.466
median: 2.742
MDWD: -0.756
low: -1465.352
 Operating Cash Flow Ratio -0.479
TIMING / LIQUIDITY
 Days Payables Outstanding (DPO) 154.192
DIVIDENDS
 Dividend Coverage Ratio
 Dividend Payout Ratio
 Dividend Rate
 Dividend Yield
PERFORMANCE GROWTH
 Asset Growth Rate -2.92 %
 Revenue Growth 44.324 %
Revenue Growth QoQ -237.324 %
Revenue Growth YoY 2122.869 %
Revenue Growth IPRWA high: 303.4 %
MDWD: 44.324 %
mean: 20.865 %
median: 12.272 %
low: -259.856 %
 Earnings Growth 1400.0 %
Earnings Growth QoQ -1837.921 %
Earnings Growth YoY -4072.984 %
Earnings Growth IPRWA MDWD: 1400.0 %
high: 155.0 %
mean: 14.868 %
median: 11.33 %
low: -175.0 %
MARGINS
 Gross Margin 23.511 %
Gross Margin QoQ 25.997 %
Gross Margin YoY 166.293 %
Gross Margin IPRWA high: 100.0 %
median: 80.103 %
mean: 77.844 %
MDWD: 23.511 %
low: -77.751 %
 EBIT Margin -100.14 %
EBIT Margin QoQ -24.2 %
EBIT Margin YoY 13.071 %
EBIT Margin IPRWA high: 338.783 %
median: 23.755 %
mean: -75.118 %
MDWD: -100.14 %
low: -5123.44 %
 Return On Sales (ROS) -100.14 %
Return On Sales QoQ -24.2 %
Return On Sales YoY 13.071 %
Return On Sales IPRWA high: 89.247 %
median: 28.85 %
mean: -78.946 %
MDWD: -100.14 %
low: -5698.0 %
CASH FLOW
 Free Cash Flow (FCF) -6.80 M
 Free Cash Flow Yield -3.374 %
Free Cash Flow Yield QoQ 28.338 %
Free Cash Flow Yield YoY -17.202 %
Free Cash Flow Yield IPRWA high: 36.371 %
median: 0.516 %
mean: -0.335 %
MDWD: -3.374 %
low: -74.318 %
 Free Cash Growth 34.247 %
Free Cash Growth QoQ -68.14 %
Free Cash Growth YoY 160.275 %
Free Cash Growth IPRWA high: 157.51 %
MDWD: 34.247 %
median: 13.256 %
mean: 3.86 %
low: -183.577 %
 Free Cash To Net Income 0.511
 Cash Flow Margin -243.921 %
 Cash Flow To Earnings 1.045
VALUE & RETURNS
 Economic Value Added 0.07
 Return On Assets (ROA) -19.583 %
Return On Assets QoQ 1821.786 %
Return On Assets YoY 85.85 %
Return On Assets IPRWA high: 36.544 %
median: 1.616 %
mean: -1.363 %
MDWD: -19.583 %
low: -68.545 %
 Return On Capital Employed (ROCE) -15.07 %
 Return On Equity (ROE) -0.662
Return On Equity QoQ 2750.818 %
Return On Equity YoY 87.604 %
Return On Equity IPRWA high: 1.117
median: 0.04
mean: 0.008
MDWD: -0.662
low: -1.572
 DuPont ROE -51.83 %
 Return On Invested Capital (ROIC) 18.533 %
Return On Invested Capital QoQ -88.138 %
Return On Invested Capital YoY -5.487 %
Return On Invested Capital IPRWA high: 53.785 %
MDWD: 18.533 %
median: 3.175 %
mean: 1.484 %
low: -71.959 %

Six-Week Outlook

Expect a catalyst‑driven range with two dominant influences: (1) operational headlines around NexoBrid manufacturing commissioning and DoD BARDA/DoD funding updates, and (2) clinical progress and site activation updates for the VALUE Phase III EscharEx trial. Technicals suggest limited upside unless volume expands — price sits below medium‑term averages despite a short‑term bounce, MACD shows a short‑term cross amid a broader momentum rollover, and MRO signals potential downward pressure from an above‑target price. Watch for enrollment or manufacturing confirmations to lift sentiment; absent clear positive headlines, the existing negative margins and negative free cash flow could pressure the stock into retesting the 50‑day/200‑day averages.

About MediWound Ltd.

MediWound Ltd. (NASDAQ:MDWD) develops and manufactures innovative biopharmaceutical solutions aimed at tissue repair and regeneration. Headquartered in Yavne, Israel, the company targets the United States, Europe, and international markets with its advanced non-surgical treatments. MediWound markets NexoBrid, a specialized product designed for the removal of eschar, or dead tissue, in adults with deep partial- and full-thickness thermal burns. This product serves burn centers and hospital burn units, providing a critical tool for effective burn care. In addition to NexoBrid, MediWound advances the development of EscharEx, a promising treatment for chronic and hard-to-heal wounds that has successfully completed Phase II clinical trials. The company also explores solutions for skin cancer with MW005, currently in Phase I/II trials for low-risk basal cell carcinoma. Since its incorporation in 2000, MediWound has committed to delivering cutting-edge therapies that address unmet medical needs in the field of wound care and beyond.



© 2025 WMDST — The World’s Most Dangerous Swing Trader. All rights reserved.