CareDx, Inc. (NASDAQ:CDNA) Reinforces Growth Prospects As Coverage Draft Advances

Momentum in short-term technicals aligns with fundamental cash strength and recent policy progress, supporting a constructive near-term profile. Operational losses persist, but several metrics point toward improving operating leverage and optionality.

Recent News

On July 18, 2025 CareDx published a proposed draft Local Coverage Determination (LCD) that would continue coverage for surveillance molecular testing for kidney, heart, and lung transplant patients without requiring a protocol biopsy, with the draft open for comment through August 31, 2025.

On July 31, 2025 CareDx highlighted landmark data presented at the 2025 World Transplant Congress and announced the launch of AlloSure® Plus integrated into EPIC Aura.

On August 6, 2025 CareDx named Nathan Smith as Chief Financial Officer, citing his experience in molecular diagnostics and financial leadership roles.

Technical Analysis

ADX at 27.77 signals a strong underlying trend; trend strength supports a measurable short-term directional bias but does not specify direction.

DI+ shows a peak-and-reversal pattern, a bearish directional signal, while DI- is decreasing, which reads as bullish; the juxtaposition suggests short-term directional conflict that often precedes a resolution move tied to momentum indicators.

MACD at 0.38 sits above its 0.18 signal line and the MACD trend increases, constituting a bullish momentum read and reinforcing short-term upside pressure on price.

MRO reads -0.35, a negative value that implies the price sits below target and therefore contains potential upside if momentum sustains.

RSI at 51.2 with an increasing trend indicates neutral-to-constructive momentum without overbought conditions; room exists for further gains before RSI reaches extended levels.

Price trades at $14.87, above the 12-day EMA ($14.51) and the 20-day average ($14.25) but remains below the 200-day average ($18.20); short-term moving averages and EMAs trending higher support near-term strength while the 200-day average marks longer-term resistance.

Bollinger bands place one-standard-deviation upper at $15.08 and lower at $13.42; the close near the upper band suggests above-average short-term volatility and proximity to resistance. The super trend lower support sits at $13.84, providing an operational short-term support reference.

 


Fundamental Analysis

Revenue for the period totaled $86,679,000, with testing services volume around 49,500 and adjusted revenue of $90.5 million as announced in the company’s second-quarter 2025 release.

Operating results remain loss-making on a GAAP basis: EBIT stood at $-10,771,000 and EBITDA at $-5,718,000, producing an operating (EBIT) margin of -12.43%. QoQ operating margin improved by +31.31% and YoY by +184.54%, signaling material sequential margin recovery despite negative absolute margins.

EPS came in at $0.10 versus an estimate of $0.12, an EPS surprise of -$0.02 or -16.67%, reflecting the GAAP loss environment for the quarter.

Cash and short-term investments total $186,255,000 and the cash ratio equals 1.999, underpinning liquidity while total debt remains modest at $29,122,000 (debt-to-assets ~6.56%). Free cash flow registered $8,888,000 with a free cash flow yield of 1.13%, above the industry peer mean free cash flow yield of 0.736%, indicating comparatively stronger cash conversion on a peer-adjusted basis.

Gross margin sits at 66.94%, above the industry peer mean of 56.97%, reflecting high protocol and service-level profitability in the company’s diagnostic business. Price multiples show a P/B of 2.40x (below the industry peer mean P/B of 4.25x) while the trailing P/E near 166x sits above the industry peer mean of about 84.83x; forward PE approximates 127.65x. Those mixed multiples reflect positive revenue traction and cash metrics but also reflect low trailing earnings and high expectations embedded in forward estimates.

Operational leverage appears to improve: asset turnover at 0.186 compares slightly above the industry peer mean of 0.159, and receivables and inventory dynamics show longer cash conversion cycle days at ~126 days versus an industry peer mean near 139 days, indicating a reasonable working-capital position relative to peers. Return on assets and equity remain negative (ROA ≈ -1.84%, ROE ≈ -2.62%) as GAAP losses persist.

WMDST values the stock as under-valued based on the supplied valuation determination; the combination of positive testing-volume growth, above-peer gross margins, ample liquidity, and improving operating margin trajectory supports that valuation stance while GAAP profitability remains the principal constraint on re-rating.

MOST-RECENT QUARTERLY REPORT
REPORT PERIOD ENDING: 2025-06-30
REPORT DATE: 2025-08-06
NEXT REPORT DATE: 2025-10-28
CASH FLOW  Begin Period Cash Flow 89.3 M
 Operating Cash Flow 9.9 M
 Capital Expenditures -1.01 M
 Change In Working Capital 3.8 M
 Dividends Paid
 Cash Flow Delta -20.53 M
 End Period Cash Flow 68.8 M
 
INCOME STATEMENT REVENUE
 Total Revenue 86.7 M
 Forward Revenue -19.52 M
COSTS
 Cost Of Revenue 28.7 M
 Depreciation 5.1 M
 Depreciation and Amortization 5.1 M
 Research and Development 16.8 M
 Total Operating Expenses 97.5 M
PROFITABILITY
 Gross Profit 58.0 M
 EBITDA -5.72 M
 EBIT -10.77 M
 Operating Income -10.77 M
 Interest Income 2.4 M
 Interest Expense
 Net Interest Income 2.4 M
 Income Before Tax -8.69 M
 Tax Provision -117.00 K
 Tax Rate 1.347 %
 Net Income -8.57 M
 Net Income From Continuing Operations -8.57 M
EARNINGS
 EPS Estimate 0.12
 EPS Actual 0.10
 EPS Difference -0.02
 EPS Surprise -16.667 %
 Forward EPS 0.14
 
BALANCE SHEET ASSETS
 Total Assets 444.3 M
 Intangible Assets 76.4 M
 Net Tangible Assets 251.0 M
 Total Current Assets 307.3 M
 Cash and Short-Term Investments 186.3 M
 Cash 68.2 M
 Net Receivables 67.4 M
 Inventory 27.9 M
 Long-Term Investments 3.3 M
LIABILITIES
 Accounts Payable 9.9 M
 Short-Term Debt
 Total Current Liabilities 93.2 M
 Net Debt
 Total Debt 29.1 M
 Total Liabilities 116.9 M
EQUITY
 Total Equity 327.4 M
 Retained Earnings -695.16 M
VALUATION & PER-SHARE METRICS EQUITY & PER-SHARE METRICS
 Book Value Per-Share 6.15
 Shares Outstanding 53.220 M
 Revenue Per-Share 1.63
VALUATION
 Market Capitalization 787.1 M
 Enterprise Value 630.0 M
 Enterprise Multiple -110.178
Enterprise Multiple QoQ -61.908 %
Enterprise Multiple YoY -117.989 %
Enterprise Multiple IPRWA high: 234.897
median: 76.655
mean: 69.27
CDNA: -110.178
low: -228.246
 EV/R 7.268
CAPITAL STRUCTURE
 Asset To Equity 1.357
 Asset To Liability 3.801
 Debt To Capital 0.082
 Debt To Assets 0.066
Debt To Assets QoQ 5.999 %
Debt To Assets YoY 404.619 %
Debt To Assets IPRWA high: 1.297
mean: 0.242
median: 0.167
CDNA: 0.066
low: 0.002
 Debt To Equity 0.089
Debt To Equity QoQ 11.465 %
Debt To Equity YoY 288.472 %
Debt To Equity IPRWA high: 2.971
mean: 0.402
median: 0.266
CDNA: 0.089
low: -1.733
PRICE-BASED VALUATION
 Price To Book (P/B) 2.404
Price To Book QoQ -16.302 %
Price To Book YoY -19.504 %
Price To Book IPRWA high: 19.098
median: 4.499
mean: 4.255
CDNA: 2.404
low: -7.981
 Price To Earnings (P/E) 166.085
Price To Earnings QoQ -23.925 %
Price To Earnings YoY 176.353 %
Price To Earnings IPRWA high: 246.592
CDNA: 166.085
median: 104.657
mean: 84.83
low: -204.468
 PE/G Ratio
 Price To Sales (P/S) 9.081
Price To Sales QoQ -29.432 %
Price To Sales YoY 5.993 %
Price To Sales IPRWA high: 154.906
mean: 20.834
median: 20.417
CDNA: 9.081
low: 0.297
FORWARD MULTIPLES
Forward P/E 127.649
Forward PE/G
Forward P/S -40.33
EFFICIENCY OPERATIONAL
 Operating Leverage 14.611
ASSET & SALES
 Asset Turnover Ratio 0.186
Asset Turnover Ratio QoQ 7.481 %
Asset Turnover Ratio YoY -7.541 %
Asset Turnover Ratio IPRWA high: 0.482
CDNA: 0.186
mean: 0.159
median: 0.135
low: 0.0
 Receivables Turnover 1.249
Receivables Turnover Ratio QoQ 0.322 %
Receivables Turnover Ratio YoY -14.546 %
Receivables Turnover Ratio IPRWA high: 3.864
mean: 1.493
median: 1.457
CDNA: 1.249
low: 0.477
 Inventory Turnover 1.127
Inventory Turnover Ratio QoQ -15.831 %
Inventory Turnover Ratio YoY -20.607 %
Inventory Turnover Ratio IPRWA high: 2.773
CDNA: 1.127
mean: 0.738
median: 0.714
low: 0.003
 Days Sales Outstanding (DSO) 73.085
CASH CYCLE
 Cash Conversion Cycle Days (CCC) 125.925
Cash Conversion Cycle Days QoQ 8.081 %
Cash Conversion Cycle Days YoY 21.29 %
Cash Conversion Cycle Days IPRWA high: 401.407
mean: 139.427
CDNA: 125.925
median: 114.45
low: -252.738
CAPITAL DEPLOYMENT
 Cash Conversion Ratio 0.405
 CapEx To Revenue -0.012
 CapEx To Depreciation -0.199
 
CAPITAL, LIQUIDITY & COVERAGE CAPITAL STRUCTURE
 Total Capital 327.4 M
 Net Invested Capital 327.4 M
 Invested Capital 327.4 M
 Net Tangible Assets 251.0 M
 Net Working Capital 214.1 M
LIQUIDITY
 Cash Ratio 1.999
 Current Ratio 3.298
Current Ratio QoQ -19.696 %
Current Ratio YoY -19.426 %
Current Ratio IPRWA high: 16.236
CDNA: 3.298
mean: 2.262
median: 1.849
low: 0.353
 Quick Ratio 2.998
Quick Ratio QoQ -21.876 %
Quick Ratio YoY -22.071 %
Quick Ratio IPRWA high: 9.867
CDNA: 2.998
mean: 1.641
median: 1.303
low: 0.411
COVERAGE & LEVERAGE
 Debt To EBITDA -5.093
 Cost Of Debt 9.537 %
 Interest Coverage Ratio -3.752
Interest Coverage Ratio QoQ 34.402 %
Interest Coverage Ratio YoY 167.271 %
Interest Coverage Ratio IPRWA high: 274.877
mean: 25.479
median: 15.82
CDNA: -3.752
low: -384.45
 Operating Cash Flow Ratio -0.028
TIMING / LIQUIDITY
 Days Payables Outstanding (DPO) 28.798
DIVIDENDS
 Dividend Coverage Ratio
 Dividend Payout Ratio
 Dividend Rate
 Dividend Yield
PERFORMANCE GROWTH
 Asset Growth Rate -9.268 %
 Revenue Growth 2.355 %
Revenue Growth QoQ -207.633 %
Revenue Growth YoY -91.611 %
Revenue Growth IPRWA high: 40.459 %
median: 7.569 %
mean: 7.495 %
CDNA: 2.355 %
low: -31.512 %
 Earnings Growth 0.0 %
Earnings Growth QoQ -100.0 %
Earnings Growth YoY -100.0 %
Earnings Growth IPRWA high: 200.0 %
median: 15.596 %
mean: 14.638 %
CDNA: 0.0 %
low: -227.273 %
MARGINS
 Gross Margin 66.938 %
Gross Margin QoQ 0.74 %
Gross Margin YoY -3.982 %
Gross Margin IPRWA high: 94.498 %
CDNA: 66.938 %
mean: 56.97 %
median: 56.435 %
low: 6.0 %
 EBIT Margin -12.426 %
EBIT Margin QoQ 31.311 %
EBIT Margin YoY 184.543 %
EBIT Margin IPRWA high: 33.87 %
median: 20.382 %
mean: 14.577 %
CDNA: -12.426 %
low: -1000.426 %
 Return On Sales (ROS) -12.426 %
Return On Sales QoQ 31.311 %
Return On Sales YoY 184.543 %
Return On Sales IPRWA high: 35.533 %
median: 18.417 %
mean: 12.936 %
CDNA: -12.426 %
low: -1349.836 %
CASH FLOW
 Free Cash Flow (FCF) 8.9 M
 Free Cash Flow Yield 1.129 %
Free Cash Flow Yield QoQ -143.608 %
Free Cash Flow Yield YoY -47.972 %
Free Cash Flow Yield IPRWA high: 11.539 %
CDNA: 1.129 %
mean: 0.736 %
median: 0.679 %
low: -40.868 %
 Free Cash Growth -131.502 %
Free Cash Growth QoQ -44.869 %
Free Cash Growth YoY -34.946 %
Free Cash Growth IPRWA high: 337.277 %
mean: 9.216 %
median: -1.288 %
CDNA: -131.502 %
low: -261.538 %
 Free Cash To Net Income -1.037
 Cash Flow Margin -2.985 %
 Cash Flow To Earnings 0.302
VALUE & RETURNS
 Economic Value Added 0.04
 Return On Assets (ROA) -1.835 %
Return On Assets QoQ -13.074 %
Return On Assets YoY 505.611 %
Return On Assets IPRWA high: 19.773 %
median: 2.151 %
mean: 1.816 %
CDNA: -1.835 %
low: -72.965 %
 Return On Capital Employed (ROCE) -3.068 %
 Return On Equity (ROE) -0.026
Return On Equity QoQ -4.104 %
Return On Equity YoY 396.584 %
Return On Equity IPRWA high: 0.769
median: 0.035
mean: 0.002
CDNA: -0.026
low: -1.731
 DuPont ROE -2.425 %
 Return On Invested Capital (ROIC) -3.246 %
Return On Invested Capital QoQ 155.994 %
Return On Invested Capital YoY -327.152 %
Return On Invested Capital IPRWA high: 20.851 %
mean: 2.939 %
median: 2.936 %
CDNA: -3.246 %
low: -30.099 %

Six-Week Outlook

Near-term price action should remain sensitive to technical confirmation: bullish momentum from MACD above its signal line and rising RSI supports continued constructive price attempts, while ADX strength indicates a directional move is plausible. Short-term support clusters align around the super trend lower ($13.84) and the 20-day average ($14.25); the 200-day average ($18.20) remains the primary longer-term resistance horizon. Fundamental catalysts to monitor include progress on the LCD coverage process and integration of AlloSure Plus into major EHR workflows, which could influence testing uptake and revenue visibility.

About CareDx, Inc.

CareDx, Inc. (NASDAQ:CDNA) develops diagnostic solutions aimed at enhancing the care and outcomes of transplant patients. Headquartered in South San Francisco, California, the company focuses on the discovery and commercialization of innovative diagnostic products. CareDx’s flagship offerings, AlloSure and AlloMap, utilize donor-derived cell-free DNA and gene expression profiling to provide critical insights into the health of transplanted organs, enabling early detection of potential rejection in kidney, heart, and lung transplants. In addition to its diagnostic tools, CareDx offers software solutions such as Ottr and XynQAPI, which streamline the management of transplant patients and ensure quality assurance. The company also provides AlloCare, a mobile application that equips patients with resources and information to manage their post-transplant journey effectively. CareDx collaborates with industry leaders to advance next-generation sequencing technologies and predictive analytics, reinforcing its dedication to innovation in transplant care. Through its comprehensive suite of products and partnerships, CareDx aims to set new standards in precision medicine, ensuring optimal care and support for transplant patients globally.



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