Keros Therapeutics, Inc (NASDAQ:KROS) Accelerates Clinical Progression And Near-Term Cash Inflow

Operational catalysts this quarter produced tangible program movement and a material cash milestone, creating a near-term catalyst set while the company maintains a defensive balance sheet. Clinical starts and partnership receipts shape a cautiously constructive immediate outlook.

Recent News

On July 30, 2026 the company announced it will receive a $20.0 million development milestone payment from partner Takeda following dosing of the first patient in the ELRiSE MDS trial; on August 3, 2026 Keros released second‑quarter 2026 results and highlighted clinical progress including initiation of a Phase 2 trial for rinvatercept in DMD; the board appointed Anne Prener effective July 1, 2026; and the company disclosed the resignation of its CFO effective August 3, 2026.

Technical Analysis

ADX registers at 24.79, indicating an emerging trend strength that supports the idea of a directional move but does not confirm a sustained, high‑strength trend.

DI+ sits at 22.86 and is decreasing, a bearish directional signal; DI− sits at 13.52 and shows a peak & reversal, a bullish directional response. Together these directional indicators present contradictory signals that favor short, catalyst‑driven swings rather than a clean trend extension.

MACD reads 0.14 with a signal line at 0.11 and shows a dip & reversal; MACD has crossed above its signal line, indicating a re‑acceleration of bullish momentum in the near term.

MRO equals −3.84 with a peak & reversal, which indicates the price sits modestly below the internal target and retains limited upside potential from that target perspective.

RSI at 51.01 and increasing signals neutral-to-positive momentum without overbought readings, leaving room for further follow‑through if clinical or partnership headlines arrive as expected.

Price sits at $11.32 above short EMAs (12‑day EMA $11.09, 26‑day EMA $10.93) and the 20‑day average ($11.10), but below the 200‑day average ($13.65), implying recent momentum yet longer‑term resistance remains. Bollinger bands place the close near the upper band (upper ~ $11.37–$11.65), consistent with short‑term upside bias but limited immediate breadth.

 


Fundamental Analysis

Liquidity and capital structure: cash and short‑term investments total $257.6M against total debt of $15.7M; the current ratio measures 2196% and the cash ratio 2119.7%, reflecting an unusually large working capital cushion versus near‑term liabilities. Total current assets $266.9M versus current liabilities $12.15M underline a strong short‑term liquidity position.

Cash flow and burn: operating cash flow for the period equals −$27.99M, free cash flow equals −$20.58M, and the reported cash decrease across the period equals −$23.89M. At that quarterly operating outflow level, cash on hand implies roughly 2.3 years of runway if run‑rate persists (cash ÷ quarterly operating outflow ≈ $257.6M ÷ $28.0M ≈ 9.2 quarters).

Profitability and expense dynamics: net loss totaled −$28.71M; operating loss (EBIT) equaled −$30.94M and EBITDA −$30.54M. Research and development expense amounted to $22.33M, reflecting continued pipeline investment as expected for a clinical‑stage biotech.

Earnings and per‑share metrics: GAAP EPS came in at −$1.45 versus an estimate of −$1.24, producing an EPS surprise of −16.94%. Forward EPS reads −$1.654 and forward PE remains negative, consistent with an early‑stage company still pre‑commercialization.

Growth rates: revenue growth reports −4.68% overall, with revenue growth year‑over‑year at −94.89% and effectively flat quarter‑over‑quarter. Reported earnings growth QoQ declined −51.26% and YoY declined −116.39%; the company’s unqualified earnings growth metric registers 19.84%, while the industry peer mean for earnings growth sits near 12.05% (industry peer mean shown for context).

Valuation metrics: price‑to‑book equals 0.83, below the industry peer mean of 8.34 and the industry peer median of 6.33; P/E metrics remain negative. Enterprise value registers negative (−$23.49M), producing an enterprise multiple of 0.77 driven by the substantial cash balance. The current valuation as determined by WMDST: over‑valued.

MOST-RECENT QUARTERLY REPORT
REPORT PERIOD ENDING: 2026-06-30
REPORT DATE: 2026-08-03
NEXT REPORT DATE: 2026-11-02
CASH FLOW  Begin Period Cash Flow 282.9 M
 Operating Cash Flow -27.98 M
 Capital Expenditures -155.00 K
 Change In Working Capital 1.9 M
 Dividends Paid
 Cash Flow Delta -23.89 M
 End Period Cash Flow 259.1 M
 
INCOME STATEMENT REVENUE
 Total Revenue
 Forward Revenue
COSTS
 Cost Of Revenue
 Depreciation 402.0 K
 Depreciation and Amortization 402.0 K
 Research and Development 22.3 M
 Total Operating Expenses 30.9 M
PROFITABILITY
 Gross Profit
 EBITDA -30.54 M
 EBIT -30.94 M
 Operating Income -30.94 M
 Interest Income
 Interest Expense
 Net Interest Income
 Income Before Tax -28.71 M
 Tax Provision
 Tax Rate
 Net Income -28.71 M
 Net Income From Continuing Operations -28.71 M
EARNINGS
 EPS Estimate -1.24
 EPS Actual -1.45
 EPS Difference -0.21
 EPS Surprise -16.935 %
 Forward EPS -1.65
 
BALANCE SHEET ASSETS
 Total Assets 287.6 M
 Intangible Assets
 Net Tangible Assets 262.3 M
 Total Current Assets 266.9 M
 Cash and Short-Term Investments 257.6 M
 Cash 257.6 M
 Net Receivables
 Inventory
 Long-Term Investments 1.4 M
LIABILITIES
 Accounts Payable 1.8 M
 Short-Term Debt
 Total Current Liabilities 12.2 M
 Net Debt
 Total Debt 15.7 M
 Total Liabilities 25.3 M
EQUITY
 Total Equity 262.3 M
 Retained Earnings -534.18 M
VALUATION & PER-SHARE METRICS EQUITY & PER-SHARE METRICS
 Book Value Per-Share 13.23
 Shares Outstanding 19.827 M
 Revenue Per-Share
VALUATION
 Market Capitalization 218.4 M
 Enterprise Value -23.49 M
 Enterprise Multiple 0.769
Enterprise Multiple QoQ 40.16 %
Enterprise Multiple YoY -65.49 %
Enterprise Multiple IPRWA high: 141.865
median: 33.436
mean: 16.851
KROS: 0.769
low: -149.487
 EV/R
CAPITAL STRUCTURE
 Asset To Equity 1.096
 Asset To Liability 11.377
 Debt To Capital 0.057
 Debt To Assets 0.055
Debt To Assets QoQ 4.672 %
Debt To Assets YoY 130.578 %
Debt To Assets IPRWA high: 0.97
mean: 0.277
median: 0.223
KROS: 0.055
low: 0.0
 Debt To Equity 0.06
Debt To Equity QoQ 4.955 %
Debt To Equity YoY 135.984 %
Debt To Equity IPRWA high: 1.687
mean: 0.296
median: 0.098
KROS: 0.06
low: -0.902
PRICE-BASED VALUATION
 Price To Book (P/B) 0.833
Price To Book QoQ -5.336 %
Price To Book YoY 0.694 %
Price To Book IPRWA high: 18.326
mean: 8.338
median: 6.334
KROS: 0.833
low: -9.25
 Price To Earnings (P/E) -7.596
Price To Earnings QoQ -27.797 %
Price To Earnings YoY -59.273 %
Price To Earnings IPRWA high: 133.654
median: 33.884
mean: 13.224
KROS: -7.596
low: -164.807
 PE/G Ratio -0.383
 Price To Sales (P/S)
Price To Sales QoQ
Price To Sales YoY
Price To Sales IPRWA
FORWARD MULTIPLES
Forward P/E -7.153
Forward PE/G -0.361
Forward P/S
EFFICIENCY OPERATIONAL
 Operating Leverage
ASSET & SALES
 Asset Turnover Ratio
Asset Turnover Ratio QoQ
Asset Turnover Ratio YoY
Asset Turnover Ratio IPRWA
 Receivables Turnover
Receivables Turnover Ratio QoQ
Receivables Turnover Ratio YoY
Receivables Turnover Ratio IPRWA
 Inventory Turnover
Inventory Turnover Ratio QoQ
Inventory Turnover Ratio YoY
Inventory Turnover Ratio IPRWA
 Days Sales Outstanding (DSO)
CASH CYCLE
 Cash Conversion Cycle Days (CCC)
Cash Conversion Cycle Days QoQ
Cash Conversion Cycle Days YoY
Cash Conversion Cycle Days IPRWA high: 564.313
median: 244.94
mean: 168.335
KROS: 0
low: -329.732
CAPITAL DEPLOYMENT
 Cash Conversion Ratio
 CapEx To Revenue
 CapEx To Depreciation -0.386
 
CAPITAL, LIQUIDITY & COVERAGE CAPITAL STRUCTURE
 Total Capital 262.3 M
 Net Invested Capital 262.3 M
 Invested Capital 262.3 M
 Net Tangible Assets 262.3 M
 Net Working Capital 254.7 M
LIQUIDITY
 Cash Ratio 21.197
 Current Ratio 21.96
Current Ratio QoQ -2.897 %
Current Ratio YoY 4.007 %
Current Ratio IPRWA high: 31.351
KROS: 21.96
mean: 5.159
median: 3.163
low: 0.048
 Quick Ratio
Quick Ratio QoQ
Quick Ratio YoY
Quick Ratio IPRWA
COVERAGE & LEVERAGE
 Debt To EBITDA -0.515
 Cost Of Debt 0.059 %
 Interest Coverage Ratio -3093.7
Interest Coverage Ratio QoQ 19.554 %
Interest Coverage Ratio YoY -22.302 %
Interest Coverage Ratio IPRWA high: 533.0
mean: 32.193
median: 1.97
low: -1501.103
KROS: -3093.7
 Operating Cash Flow Ratio -2.303
TIMING / LIQUIDITY
 Days Payables Outstanding (DPO)
DIVIDENDS
 Dividend Coverage Ratio
 Dividend Payout Ratio
 Dividend Rate
 Dividend Yield
PERFORMANCE GROWTH
 Asset Growth Rate -7.907 %
 Revenue Growth -4.675 %
Revenue Growth QoQ -0.0 %
Revenue Growth YoY -94.885 %
Revenue Growth IPRWA high: 330.841 %
mean: 15.858 %
median: 10.794 %
KROS: -4.675 %
low: -242.388 %
 Earnings Growth 19.835 %
Earnings Growth QoQ -51.263 %
Earnings Growth YoY -116.393 %
Earnings Growth IPRWA high: 175.0 %
KROS: 19.835 %
median: 12.5 %
mean: 12.052 %
low: -155.294 %
MARGINS
 Gross Margin
Gross Margin QoQ
Gross Margin YoY
Gross Margin IPRWA
 EBIT Margin
EBIT Margin QoQ
EBIT Margin YoY
EBIT Margin IPRWA
 Return On Sales (ROS)
Return On Sales QoQ
Return On Sales YoY
Return On Sales IPRWA
CASH FLOW
 Free Cash Flow (FCF) -20.58 M
 Free Cash Flow Yield -9.422 %
Free Cash Flow Yield QoQ 557.043 %
Free Cash Flow Yield YoY 81.437 %
Free Cash Flow Yield IPRWA high: 13.067 %
median: 0.852 %
mean: 0.445 %
KROS: -9.422 %
low: -34.637 %
 Free Cash Growth 471.238 %
Free Cash Growth QoQ -642.488 %
Free Cash Growth YoY -496.355 %
Free Cash Growth IPRWA KROS: 471.238 %
high: 175.34 %
mean: 19.379 %
median: 1.424 %
low: -209.632 %
 Free Cash To Net Income 0.717
 Cash Flow Margin
 Cash Flow To Earnings 0.975
VALUE & RETURNS
 Economic Value Added
 Return On Assets (ROA) -9.572 %
Return On Assets QoQ 31.285 %
Return On Assets YoY 140.382 %
Return On Assets IPRWA high: 24.482 %
median: 0.09 %
mean: -4.334 %
KROS: -9.572 %
low: -52.406 %
 Return On Capital Employed (ROCE) -11.232 %
 Return On Equity (ROE) -0.109
Return On Equity QoQ 31.867 %
Return On Equity YoY 152.015 %
Return On Equity IPRWA high: 0.542
median: 0.005
mean: -0.104
KROS: -0.109
low: -0.887
 DuPont ROE
 Return On Invested Capital (ROIC)
Return On Invested Capital QoQ
Return On Invested Capital YoY
Return On Invested Capital IPRWA

Six-Week Outlook

Near‑term price drivers center on clinical progress and partnership milestones already in motion. Technicals favor modest upside momentum—MACD crossed above its signal and short EMAs trend higher—while directional indicators conflict, increasing the likelihood of headline‑sensitive swings. Strong cash reserves and the $20M milestone reduce financing risk over the next several quarters, limiting downside from liquidity pressure but not eliminating binary clinical or execution risk. Expect elevated event-driven volatility; momentum currently biases toward measured gains but reactive pullbacks remain possible if clinical signage or management changes disappoint. The next material reporting cadence includes the company’s scheduled report on November 2, 2026, which could re‑set the short‑term technical posture.

About Keros Therapeutics, Inc.

Keros Therapeutics, Inc. (NASDAQ:KROS) develops and commercializes innovative therapeutics targeting disorders associated with dysfunctional signaling of the transforming growth factor-beta family of proteins. Headquartered in Lexington, Massachusetts, this clinical-stage biopharmaceutical company advances its lead product candidate, KER-050, aimed at treating cytopenias, including anemia and thrombocytopenia, particularly in patients with myelodysplastic syndromes and myelofibrosis. Keros Therapeutics also progresses with KER-012, currently in Phase II clinical trials, designed to address pulmonary arterial hypertension and cardiovascular disorders. Additionally, KER-065 enters Phase I clinical trials targeting obesity and neuromuscular diseases. The company collaborates with Hansoh (Shanghai) Healthtech Co., Ltd., enhancing its capabilities to develop, manufacture, and commercialize KER-050 and related licensed products. Founded in 2015, Keros Therapeutics commits to advancing its pipeline and addressing unmet medical needs through targeted therapeutic development.



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