Illumina, Inc. (NASDAQ:ILMN) Poised For Near-Term Pullback Despite Uptrend

Momentum and breadth show mixed signals: underlying business metrics hold but short-term momentum weakens, setting conditions for a near-term consolidation while the longer-term trend stays constructive.

Recent News

June 23: Illumina appointed Daniel M. Skovronsky, MD, PhD, to its board. June 8: the company launched StrataMap Spatial, an end-to-end spatial whole-transcriptome research solution. May 28: Illumina announced workflow integrations and a new targeted oncology kit with Pillar Biosciences. May 19: the company published its 2025 Corporate Responsibility Report outlining expanded access and community initiatives. July 9: Illumina announced a senior commercial leadership change, naming a new Chief Commercial Officer effective July 20, 2026.

Technical Analysis

ADX registers 35.66, indicating a strong directional regime in place; that strength raises the significance of any directional shift.

DI+ sits at 27.32 and is decreasing while DI– reads 13.77 and is increasing — the directional indicators together point to a bearish shift in trend.

MACD equals 6.84, is decreasing, and remains below its signal line (7.72), signaling bearish momentum rather than a bullish crossover.

MRO stands at 33.21 with a dip & reversal; the oscillator’s positive reading implies price sits above the model target and faces mean-reversion pressure.

RSI at 64.52 shows momentum cooling and the RSI trend is decreasing, leaving less room for sustained near-term upside.

Price rests above short- and long-term averages (12-day EMA rising at $187.98; 20-day average $189.99; 50-day average $167.90; 200-day average $136.21), which supports the longer-term bullish bias even as short-term momentum indicators weaken.

Price trades near the upper Bollinger band (upper 1σ ~$193.08) with volume slightly above the 10-day average but below longer-term averages, suggesting recent moves lack strong participation. SuperTrend lower support aligns near $177.00 and the Ichimoku Tenkan/Kijun levels sit at $187.77 / $177.15 respectively, the former nearer to current price and implying short-term support around those levels.

 


Fundamental Analysis

Profitability: gross margin stands at 66.09% (QoQ +0.92%, YoY +0.73%). Operating margin registers 19.16% and EBIT margin measures 16.59%; EBIT margin QoQ declined by 52.29% and YoY declined by 16.57%. The EBIT margin sits above the industry peer mean of 13.63% but below the industry peer median of 18.97%.

Growth and earnings: total revenue equals $1.091 billion with revenue growth year‑over‑year of +2.80% and a quarter‑over‑quarter change of -184.80%. Reported EPS came in at $1.15 versus an estimate of $1.05, producing an EPS surprise of +9.52%. Reported net income reached $134.0 million. Earnings growth measures -14.82% on the primary growth metric and the year‑over‑year earnings change reads -215.82% on the provided YoY field.

Cash flow and liquidity: operating cash flow equals $250.0 million and free cash flow totals $251.0 million, yielding a free cash flow yield of 1.30% and a free cash flow to net income ratio of 1.87. Cash and short‑term investments total $1.155 billion; the current ratio stands at 1.75 and the quick ratio at 1.36.

Capital structure and coverage: total debt equals $2.544 billion with net debt near $900.0 million. Debt to EBITDA registers about 10.18x while interest coverage equals 7.54x. Return on equity reads 5.01% and return on assets 2.03%.

Valuation snapshot: trailing P/E about 110.5x, forward P/E about 86.7x, price-to-sales near 17.7x, and price-to-book about 7.22x; enterprise value approximates $20.70 billion. The current valuation, as determined by WMDST, classifies the stock as under-valued despite elevated multiples on common market metrics.

MOST-RECENT QUARTERLY REPORT
REPORT PERIOD ENDING: 2026-03-31
REPORT DATE: 2026-04-30
NEXT REPORT DATE: 2026-07-30
CASH FLOW  Begin Period Cash Flow 1.4 B
 Operating Cash Flow 250.0 M
 Capital Expenditures -38.00 M
 Change In Working Capital -1.00 M
 Dividends Paid
 Cash Flow Delta -329.00 M
 End Period Cash Flow 1.1 B
 
INCOME STATEMENT REVENUE
 Total Revenue 1.1 B
 Forward Revenue 457.2 M
COSTS
 Cost Of Revenue 370.0 M
 Depreciation 51.0 M
 Depreciation and Amortization 69.0 M
 Research and Development 240.0 M
 Total Operating Expenses 882.0 M
PROFITABILITY
 Gross Profit 721.0 M
 EBITDA 250.0 M
 EBIT 181.0 M
 Operating Income 209.0 M
 Interest Income 11.0 M
 Interest Expense 24.0 M
 Net Interest Income -13.00 M
 Income Before Tax 157.0 M
 Tax Provision 23.0 M
 Tax Rate 14.65 %
 Net Income 134.0 M
 Net Income From Continuing Operations 134.0 M
EARNINGS
 EPS Estimate 1.05
 EPS Actual 1.15
 EPS Difference 0.10
 EPS Surprise 9.524 %
 Forward EPS 1.48
 
BALANCE SHEET ASSETS
 Total Assets 6.6 B
 Intangible Assets 1.7 B
 Net Tangible Assets 962.0 M
 Total Current Assets 2.7 B
 Cash and Short-Term Investments 1.2 B
 Cash 1.1 B
 Net Receivables 738.0 M
 Inventory 611.0 M
 Long-Term Investments 523.0 M
LIABILITIES
 Accounts Payable 218.0 M
 Short-Term Debt 499.0 M
 Total Current Liabilities 1.6 B
 Net Debt 900.0 M
 Total Debt 2.5 B
 Total Liabilities 3.9 B
EQUITY
 Total Equity 2.7 B
 Retained Earnings -258.00 M
VALUATION & PER-SHARE METRICS EQUITY & PER-SHARE METRICS
 Book Value Per-Share 17.61
 Shares Outstanding 152.000 M
 Revenue Per-Share 7.18
VALUATION
 Market Capitalization 19.3 B
 Enterprise Value 20.7 B
 Enterprise Multiple 82.81
Enterprise Multiple QoQ 81.626 %
Enterprise Multiple YoY 48.899 %
Enterprise Multiple IPRWA high: 221.771
mean: 84.153
ILMN: 82.81
median: 82.306
low: -94.625
 EV/R 18.976
CAPITAL STRUCTURE
 Asset To Equity 2.451
 Asset To Liability 1.689
 Debt To Capital 0.487
 Debt To Assets 0.388
Debt To Assets QoQ 0.937 %
Debt To Assets YoY -8.027 %
Debt To Assets IPRWA high: 0.694
ILMN: 0.388
median: 0.381
mean: 0.337
low: 0.046
 Debt To Equity 0.951
Debt To Equity QoQ 1.397 %
Debt To Equity YoY -13.648 %
Debt To Equity IPRWA high: 1.28
ILMN: 0.951
median: 0.831
mean: 0.712
low: 0.053
PRICE-BASED VALUATION
 Price To Book (P/B) 7.217
Price To Book QoQ -3.962 %
Price To Book YoY 22.253 %
Price To Book IPRWA ILMN: 7.217
high: 6.871
mean: 3.857
median: 3.707
low: 0.163
 Price To Earnings (P/E) 110.489
Price To Earnings QoQ 11.524 %
Price To Earnings YoY 21.896 %
Price To Earnings IPRWA high: 338.717
ILMN: 110.489
mean: 96.052
median: 95.233
low: -211.689
 PE/G Ratio -7.458
 Price To Sales (P/S) 17.703
Price To Sales QoQ 0.263 %
Price To Sales YoY 31.822 %
Price To Sales IPRWA high: 36.903
mean: 18.548
ILMN: 17.703
median: 17.494
low: 0.107
FORWARD MULTIPLES
Forward P/E 86.693
Forward PE/G -5.852
Forward P/S 42.239
EFFICIENCY OPERATIONAL
 Operating Leverage 9.389
ASSET & SALES
 Asset Turnover Ratio 0.165
Asset Turnover Ratio QoQ -8.59 %
Asset Turnover Ratio YoY -0.893 %
Asset Turnover Ratio IPRWA high: 0.168
ILMN: 0.165
mean: 0.105
median: 0.098
low: 0.035
 Receivables Turnover 1.371
Receivables Turnover Ratio QoQ -6.4 %
Receivables Turnover Ratio YoY -5.598 %
Receivables Turnover Ratio IPRWA high: 3.506
ILMN: 1.371
mean: 1.284
median: 1.216
low: 1.147
 Inventory Turnover 0.63
Inventory Turnover Ratio QoQ -9.153 %
Inventory Turnover Ratio YoY -4.652 %
Inventory Turnover Ratio IPRWA high: 2.484
median: 1.204
mean: 1.094
ILMN: 0.63
low: 0.207
 Days Sales Outstanding (DSO) 66.577
CASH CYCLE
 Cash Conversion Cycle Days (CCC) 148.359
Cash Conversion Cycle Days QoQ -2.897 %
Cash Conversion Cycle Days YoY 4.148 %
Cash Conversion Cycle Days IPRWA high: 393.16
ILMN: 148.359
mean: 114.964
median: 100.104
low: 42.31
CAPITAL DEPLOYMENT
 Cash Conversion Ratio 0.931
 CapEx To Revenue -0.035
 CapEx To Depreciation -0.745
 
CAPITAL, LIQUIDITY & COVERAGE CAPITAL STRUCTURE
 Total Capital 4.2 B
 Net Invested Capital 4.7 B
 Invested Capital 4.7 B
 Net Tangible Assets 962.0 M
 Net Working Capital 1.2 B
LIQUIDITY
 Cash Ratio 0.738
 Current Ratio 1.748
Current Ratio QoQ -15.743 %
Current Ratio YoY -5.81 %
Current Ratio IPRWA high: 12.356
mean: 2.089
ILMN: 1.748
median: 1.526
low: 0.267
 Quick Ratio 1.358
Quick Ratio QoQ -20.998 %
Quick Ratio YoY -8.433 %
Quick Ratio IPRWA high: 11.915
mean: 1.609
ILMN: 1.358
median: 1.15
low: 0.211
COVERAGE & LEVERAGE
 Debt To EBITDA 10.176
 Cost Of Debt 0.898 %
 Interest Coverage Ratio 7.542
Interest Coverage Ratio QoQ -51.344 %
Interest Coverage Ratio YoY -8.917 %
Interest Coverage Ratio IPRWA high: 30.652
ILMN: 7.542
median: 5.898
mean: 2.918
low: -270.336
 Operating Cash Flow Ratio 0.16
TIMING / LIQUIDITY
 Days Payables Outstanding (DPO) 52.241
DIVIDENDS
 Dividend Coverage Ratio
 Dividend Payout Ratio
 Dividend Rate
 Dividend Yield
PERFORMANCE GROWTH
 Asset Growth Rate -1.279 %
 Revenue Growth -5.867 %
Revenue Growth QoQ -184.795 %
Revenue Growth YoY 2.804 %
Revenue Growth IPRWA high: 32.205 %
ILMN: -5.867 %
mean: -7.832 %
median: -9.906 %
low: -16.725 %
 Earnings Growth -14.815 %
Earnings Growth QoQ -2085.925 %
Earnings Growth YoY -215.824 %
Earnings Growth IPRWA high: 108.696 %
mean: -12.136 %
ILMN: -14.815 %
median: -17.199 %
low: -140.0 %
MARGINS
 Gross Margin 66.086 %
Gross Margin QoQ 0.915 %
Gross Margin YoY 0.725 %
Gross Margin IPRWA high: 83.743 %
ILMN: 66.086 %
mean: 44.337 %
median: 40.254 %
low: 4.636 %
 EBIT Margin 16.59 %
EBIT Margin QoQ -52.288 %
EBIT Margin YoY -16.57 %
EBIT Margin IPRWA high: 23.643 %
median: 18.973 %
ILMN: 16.59 %
mean: 13.628 %
low: -170.307 %
 Return On Sales (ROS) 19.157 %
Return On Sales QoQ 5.229 %
Return On Sales YoY -3.661 %
Return On Sales IPRWA high: 24.243 %
ILMN: 19.157 %
median: 17.383 %
mean: 15.973 %
low: -173.107 %
CASH FLOW
 Free Cash Flow (FCF) 251.0 M
 Free Cash Flow Yield 1.3 %
Free Cash Flow Yield QoQ 0.0 %
Free Cash Flow Yield YoY -9.597 %
Free Cash Flow Yield IPRWA ILMN: 1.3 %
high: 1.021 %
median: 0.424 %
mean: 0.382 %
low: -25.298 %
 Free Cash Growth -5.639 %
Free Cash Growth QoQ -344.324 %
Free Cash Growth YoY -85.903 %
Free Cash Growth IPRWA high: 362.912 %
ILMN: -5.639 %
mean: -64.217 %
median: -72.727 %
low: -125.322 %
 Free Cash To Net Income 1.873
 Cash Flow Margin 22.915 %
 Cash Flow To Earnings 1.866
VALUE & RETURNS
 Economic Value Added 0.04
 Return On Assets (ROA) 2.03 %
Return On Assets QoQ -61.036 %
Return On Assets YoY -3.287 %
Return On Assets IPRWA high: 2.388 %
ILMN: 2.03 %
median: 1.477 %
mean: 1.189 %
low: -20.807 %
 Return On Capital Employed (ROCE) 3.625 %
 Return On Equity (ROE) 0.05
Return On Equity QoQ -59.18 %
Return On Equity YoY -9.49 %
Return On Equity IPRWA high: 0.226
ILMN: 0.05
median: 0.032
mean: 0.026
low: -0.7
 DuPont ROE 4.964 %
 Return On Invested Capital (ROIC) 3.312 %
Return On Invested Capital QoQ -56.289 %
Return On Invested Capital YoY -3.13 %
Return On Invested Capital IPRWA ILMN: 3.312 %
high: 3.177 %
median: 2.107 %
mean: 1.763 %
low: -10.359 %

Six-Week Outlook

Near-term bias: consolidation with downside risk. Technicals show a strong regime (ADX) but directional indicators and MACD favor a pullback or range-bound chop before any clear resumption of the advance. MRO’s positive dip & reversal warns of mean reversion pressure while RSI’s decline signals waning upside momentum.

Key watch-points for the next six weeks: whether DI+ stabilizes or resumes increasing (would re-validate upside), a MACD turn back up and cross above its signal (would shift momentum bullish), and MRO moving back toward zero (would reduce mean‑reversion risk). Hold levels around the SuperTrend lower near $177 and the Ichimoku Kijun at $177.15 provide reference points for where short-term support currently concentrates; upside scenarios reconnect to the analyst price target mean near $242 if momentum indicators reverse. Volatility remains muted on 42- and 52-week measures, so directional moves may require a clear momentum shift to sustain.

About Illumina, Inc.

Illumina, Inc. (NASDAQ:ILMN) develops and supplies advanced genetic and genomic analysis tools. Based in San Diego, California, the company offers a wide range of sequencing and array-based solutions that address various genomic needs. Illumina’s portfolio includes high-performance sequencing instruments, essential reagents, and consumables, as well as comprehensive whole-genome and targeted resequencing kits. The company’s technological advancements support critical healthcare applications, including noninvasive prenatal testing and cancer diagnostics, such as the Galleri multi-cancer early detection test. Illumina’s innovations facilitate the detection of minimal residual disease through blood-based diagnostics, contributing to improved post-diagnostic care. Illumina serves a diverse clientele, including genomic research centers, academic institutions, and companies in the pharmaceutical and biotechnology sectors. By distributing its products directly and through life-science distributors, Illumina aims to advance scientific discovery and enhance human health globally. Through its Core Illumina and GRAIL segments, the company continues to lead in the development of technologies that drive progress in genomics.



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