Scholar Rock Holding Corporation (NASDAQ:SRRK) Eyes Repricing As FDA Review Nears Late-September

Upcoming regulatory milestones concentrate near-term attention on the company while balance-sheet strength cushions operational runway. The combination of a resubmitted BLA and mixed technical momentum sets a catalyst-driven, range-bound near-term profile.

Recent News

On March 31, 2026 the company announced resubmission of the Biologics License Application (BLA) for apitegromab and stated FDA acceptance was expected within 30 days, with a PDUFA action date projected in late September 2026 (company disclosure). On May 7, 2026 Scholar Rock published first-quarter 2026 financial results and business highlights, noting commercial supply readiness efforts and an expectation that a second U.S.-based fill-finish facility would deliver additional product ahead of the PDUFA timeline. The May release reconfirmed a September 30, 2026 PDUFA action date in its forward-looking statements.

Technical Analysis

ADX at 15.67 indicates no established trend; directional signals lack strength despite conflicting short-term directional cues, so price action should remain susceptible to catalyst-driven moves rather than sustained technical trends.

DI+ shows a dip-and-reversal while DI- shows a peak-and-reversal, each signaling bullish directional readings; absent ADX confirmation, these directional readings imply potential upside into a catalyst but limited conviction for a sustained breakout.

MACD sits negative at -0.80 with a decreasing MACD_trend and a signal line at -0.35; negative and declining MACD indicates bearish momentum and no bullish MACD/signal cross has occurred to support a short-term trend reversal.

MRO at 12.15 and decreasing indicates the current price sits above the WMDST target and places downward pressure on price toward the valuation level; the positive MRO implies mean-reversion risk into the valuation anchor.

RSI at 48.07 and decreasing registers near-neutral with a modest downward bias, consistent with consolidation rather than a clear overbought or oversold condition.

Price trades below short- and medium-term averages (price vs 20‑day ~ $46.71, 50‑day ~ $47.88, 26‑day EMA ~ $46.70) while holding above the 200‑day average ($41.81); short-term averages pulling above price reinforce near-term downside friction, while the 200‑day level offers structural support relative to longer-term trend.

Ichimoku components place price beneath the cloud (Senkou A $47.01 / Senkou B $45.19), reinforcing a short-term bearish posture until price reclaims cloud levels; price sits roughly $1.00 above the 1× lower Bollinger band ($43.69), signaling proximity to the short-term lower boundary of the recent range.

Volume at ~959,949 sits below 10/50/200‑day averages, indicating low participation; muted volume reduces the odds of conviction-led moves absent a fundamental catalyst such as regulatory news or supply updates.

 


Fundamental Analysis

Profitability metrics remain negative: EBIT at -$103,208,000, EBITDA at -$102,873,000, and net income at -$105,510,000, with EPS actual of -$0.83 versus an estimate of -$0.78 (EPS surprise -6.41%). These operating losses keep valuation multiples distorted and produce a negative enterprise multiple.

Cash position strong: $430,543,000 in cash and $479,944,000 in cash and short‑term investments, paired with total current assets of $515,284,000 and total current liabilities of $59,643,000, produces a current ratio of 8.64 and a cash ratio of 8.05, indicating ample liquidity to fund near-term operations and regulatory activities.

Free cash flow remains negative at -$82,169,000 with a free cash flow yield of -1.50% and operating cash flow at -$106,260,000, signaling continuing cash consumption tied to development activities despite the cash balance.

Balance sheet leverage sits at total debt $205,674,000 versus total equity $276,013,000 (debt-to-equity 0.75 and debt-to-assets 0.38); debt levels remain manageable relative to liquidity but increased debt ratios QoQ and YoY suggest financing and capital-structure dynamics to monitor.

Valuation multiples present material dispersion. Price-to-book stands at 19.89, which sits above the industry peer mean (≈7.48) and median (≈5.47) and approaches the top of the industry peer range (high ≈20.84), while PEG and forward PE remain negative or high due to loss-making status. WMDST values the stock as under-valued; the valuation call reflects the cash-adjusted enterprise picture and risk-reduction from regulatory alignment but remains contingent on successful regulatory outcome and subsequent commercial execution.

MOST-RECENT QUARTERLY REPORT
REPORT PERIOD ENDING: 2026-03-31
REPORT DATE: 2026-05-07
NEXT REPORT DATE: 2026-08-06
CASH FLOW  Begin Period Cash Flow 327.3 M
 Operating Cash Flow -106.26 M
 Capital Expenditures -68.00 K
 Change In Working Capital 84.0 K
 Dividends Paid
 Cash Flow Delta 107.0 M
 End Period Cash Flow 434.4 M
 
INCOME STATEMENT REVENUE
 Total Revenue
 Forward Revenue
COSTS
 Cost Of Revenue
 Depreciation 335.0 K
 Depreciation and Amortization 335.0 K
 Research and Development 51.8 M
 Total Operating Expenses 102.0 M
PROFITABILITY
 Gross Profit
 EBITDA -102.87 M
 EBIT -103.21 M
 Operating Income -102.02 M
 Interest Income 2.9 M
 Interest Expense 2.3 M
 Net Interest Income 633.0 K
 Income Before Tax -105.51 M
 Tax Provision
 Tax Rate
 Net Income -105.51 M
 Net Income From Continuing Operations -105.51 M
EARNINGS
 EPS Estimate -0.78
 EPS Actual -0.83
 EPS Difference -0.05
 EPS Surprise -6.41 %
 Forward EPS -0.59
 
BALANCE SHEET ASSETS
 Total Assets 535.3 M
 Intangible Assets
 Net Tangible Assets 276.0 M
 Total Current Assets 515.3 M
 Cash and Short-Term Investments 479.9 M
 Cash 430.5 M
 Net Receivables
 Inventory
 Long-Term Investments 3.8 M
LIABILITIES
 Accounts Payable 9.2 M
 Short-Term Debt
 Total Current Liabilities 59.6 M
 Net Debt
 Total Debt 205.7 M
 Total Liabilities 259.2 M
EQUITY
 Total Equity 276.0 M
 Retained Earnings -1.41 B
VALUATION & PER-SHARE METRICS EQUITY & PER-SHARE METRICS
 Book Value Per-Share 2.32
 Shares Outstanding 119.104 M
 Revenue Per-Share
VALUATION
 Market Capitalization 5.5 B
 Enterprise Value 5.2 B
 Enterprise Multiple -50.71
Enterprise Multiple QoQ -1.084 %
Enterprise Multiple YoY 38.292 %
Enterprise Multiple IPRWA high: 75.51
median: 27.492
mean: 9.622
SRRK: -50.71
low: -126.596
 EV/R
CAPITAL STRUCTURE
 Asset To Equity 1.939
 Asset To Liability 2.065
 Debt To Capital 0.427
 Debt To Assets 0.384
Debt To Assets QoQ 42.626 %
Debt To Assets YoY 148.015 %
Debt To Assets IPRWA high: 1.112
SRRK: 0.384
mean: 0.167
median: 0.031
low: 0.0
 Debt To Equity 0.745
Debt To Equity QoQ 67.954 %
Debt To Equity YoY 268.581 %
Debt To Equity IPRWA high: 1.864
SRRK: 0.745
mean: 0.191
median: 0.051
low: -1.199
PRICE-BASED VALUATION
 Price To Book (P/B) 19.894
Price To Book QoQ 2.377 %
Price To Book YoY 99.558 %
Price To Book IPRWA high: 20.844
SRRK: 19.894
mean: 7.482
median: 5.469
low: -11.267
 Price To Earnings (P/E) -55.545
Price To Earnings QoQ 11.136 %
Price To Earnings YoY 13.396 %
Price To Earnings IPRWA high: 74.242
mean: -1.84
median: -14.301
SRRK: -55.545
low: -121.28
 PE/G Ratio 9.776
 Price To Sales (P/S)
Price To Sales QoQ
Price To Sales YoY
Price To Sales IPRWA
FORWARD MULTIPLES
Forward P/E -72.663
Forward PE/G 12.788
Forward P/S
EFFICIENCY OPERATIONAL
 Operating Leverage
ASSET & SALES
 Asset Turnover Ratio
Asset Turnover Ratio QoQ
Asset Turnover Ratio YoY
Asset Turnover Ratio IPRWA
 Receivables Turnover
Receivables Turnover Ratio QoQ
Receivables Turnover Ratio YoY
Receivables Turnover Ratio IPRWA
 Inventory Turnover
Inventory Turnover Ratio QoQ
Inventory Turnover Ratio YoY
Inventory Turnover Ratio IPRWA
 Days Sales Outstanding (DSO)
CASH CYCLE
 Cash Conversion Cycle Days (CCC)
Cash Conversion Cycle Days QoQ
Cash Conversion Cycle Days YoY
Cash Conversion Cycle Days IPRWA high: 499.798
mean: 219.741
median: 208.031
SRRK: 0
low: -303.652
CAPITAL DEPLOYMENT
 Cash Conversion Ratio
 CapEx To Revenue
 CapEx To Depreciation -0.203
 
CAPITAL, LIQUIDITY & COVERAGE CAPITAL STRUCTURE
 Total Capital 472.6 M
 Net Invested Capital 472.6 M
 Invested Capital 472.6 M
 Net Tangible Assets 276.0 M
 Net Working Capital 455.6 M
LIQUIDITY
 Cash Ratio 8.047
 Current Ratio 8.639
Current Ratio QoQ 24.314 %
Current Ratio YoY -15.737 %
Current Ratio IPRWA high: 32.587
SRRK: 8.639
mean: 3.935
median: 2.409
low: 0.016
 Quick Ratio
Quick Ratio QoQ
Quick Ratio YoY
Quick Ratio IPRWA
COVERAGE & LEVERAGE
 Debt To EBITDA -1.999
 Cost Of Debt 1.463 %
 Interest Coverage Ratio -44.834
Interest Coverage Ratio QoQ 28.472 %
Interest Coverage Ratio YoY -34.281 %
Interest Coverage Ratio IPRWA high: 604.866
median: -14.753
SRRK: -44.834
mean: -77.316
low: -1643.72
 Operating Cash Flow Ratio -1.782
TIMING / LIQUIDITY
 Days Payables Outstanding (DPO)
DIVIDENDS
 Dividend Coverage Ratio
 Dividend Payout Ratio
 Dividend Rate
 Dividend Yield
PERFORMANCE GROWTH
 Asset Growth Rate 32.399 %
 Revenue Growth
Revenue Growth QoQ
Revenue Growth YoY
Revenue Growth IPRWA
 Earnings Growth -5.682 %
Earnings Growth QoQ 155.716 %
Earnings Growth YoY -157.767 %
Earnings Growth IPRWA high: 200.0 %
median: -5.479 %
SRRK: -5.682 %
mean: -13.779 %
low: -250.0 %
MARGINS
 Gross Margin
Gross Margin QoQ
Gross Margin YoY
Gross Margin IPRWA
 EBIT Margin
EBIT Margin QoQ
EBIT Margin YoY
EBIT Margin IPRWA
 Return On Sales (ROS)
Return On Sales QoQ
Return On Sales YoY
Return On Sales IPRWA
CASH FLOW
 Free Cash Flow (FCF) -82.17 M
 Free Cash Flow Yield -1.496 %
Free Cash Flow Yield QoQ -5.496 %
Free Cash Flow Yield YoY -41.009 %
Free Cash Flow Yield IPRWA high: 11.709 %
median: 0.11 %
mean: -0.511 %
SRRK: -1.496 %
low: -45.34 %
 Free Cash Growth 8.793 %
Free Cash Growth QoQ -6.952 %
Free Cash Growth YoY -85.19 %
Free Cash Growth IPRWA high: 253.163 %
SRRK: 8.793 %
mean: 4.256 %
median: -16.897 %
low: -249.577 %
 Free Cash To Net Income 0.779
 Cash Flow Margin
 Cash Flow To Earnings 1.007
VALUE & RETURNS
 Economic Value Added
 Return On Assets (ROA) -22.46 %
Return On Assets QoQ 0.736 %
Return On Assets YoY 32.625 %
Return On Assets IPRWA high: 38.074 %
median: -7.986 %
mean: -13.724 %
SRRK: -22.46 %
low: -67.817 %
 Return On Capital Employed (ROCE) -21.7 %
 Return On Equity (ROE) -0.382
Return On Equity QoQ 3.16 %
Return On Equity YoY 59.781 %
Return On Equity IPRWA high: 0.797
median: -0.11
mean: -0.344
SRRK: -0.382
low: -1.265
 DuPont ROE
 Return On Invested Capital (ROIC)
Return On Invested Capital QoQ
Return On Invested Capital YoY
Return On Invested Capital IPRWA

Six-Week Outlook

Expect consolidation inside the current short-term band with bias toward downside testing absent a news catalyst. Technical momentum currently tilts bearish (negative MACD, declining RSI, price below short-term averages) while directional indicators show bullish flips without ADX confirmation; that combination predisposes price to range-bound trading and mean reversion toward the WMDST valuation level. Volume will serve as the key confirmatory variable—an uptick tied to regulatory or supply updates should drive decisive moves, while continued low participation increases the likelihood of price chopping near current levels. Monitor MRO and MACD for early signs of momentum improvement before anticipating sustained directional movement.

About Scholar Rock Holding Corporation

Scholar Rock Holding Corporation (NASDAQ:SRRK) develops innovative biopharmaceutical solutions targeting serious diseases influenced by protein growth factor signaling. The company advances Apitegromab, a myostatin activation inhibitor, currently undergoing Phase 3 clinical trials aimed at treating spinal muscular atrophy. Scholar Rock also progresses SRK-181, which has completed Phase 1 trials, targeting cancers resistant to checkpoint inhibitor therapies, including anti-PD-1 and anti-PD-L1 antibody therapies. Their pipeline includes potential treatments for neuromuscular disorders, cardiometabolic disorders, cancer, fibrosis, and iron-restricted anemia. Founded in 2012, Scholar Rock operates from its headquarters in Cambridge, Massachusetts, driving forward the development of novel therapeutic candidates to address unmet medical needs.



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