Recent News
On July 7, 2025 the company shortened Express turnaround times for all gene fragments, offering two-business-day shipping and standardized pricing. On July 24, 2025 Twist announced inducement equity grants totaling 70,254 awards to recently hired personnel. Early August filings show several executives sold shares on August 4, 2025. Mid-August 2025 reporting indicated Invesco reduced its position by 200,205 shares. In early September 2025 the CEO scheduled presentations at the Baird 2025 Global Healthcare Conference and Morgan Stanley investor meetings.
Technical Analysis
Directional indicators show a lack of a clear trend: ADX at 16.9 signals no trend, while DI+ peaked-and-reversed and DI- dipped-and-reversed, producing a bearish directional bias that weakens conviction for sustained trend continuation.
MACD sits at -$0.38 and trades above its signal line at -$0.66, with an increasing MACD trend; that cross indicates improving bullish momentum from a negative baseline and supports a near-term bounce narrative.
MRO registers -16.28, indicating price sits below the model target and may move higher toward that target; the magnitude implies a measurable—but not extreme—mean-reversion potential if momentum confirms.
RSI at 44.5 and rising reflects building conviction without overbought pressure; momentum remains constructive only if RSI breaches mid-range levels on follow-through volume.
Price sits at $27.00, above the 20-day average ($26.70) but below the 50-day ($28.55) and 200-day ($37.36), which places the stock in a short-term recovery inside a longer-term downtrend. The 12-day EMA shows a peak-and-reversal pattern, adding short-term bearish friction until investors push price back above the 50-day average.
Bollinger bands place the 1x upper band at $27.95 with current price inside the upper band, suggesting limited immediate upside without a volatility expansion. Ichimoku components (Senkou A $30.52, Senkou B $31.82) keep price beneath the cloud, implying overhead resistance until price reclaims the cloud. The super trend upper at $28.13 sits as a near-term resistance level to watch.
Fundamental Analysis
Profitability shows operating pressure: operating income and EBIT both sit at -$30,120,000 and operating margin equals -31.356%. Operating margin declined QoQ by -25.41% and YoY by -70.08%. The operating margin sits below the industry peer mean of 19.345% and below the industry peer median of 19.467%, while remaining above the industry peer low of -167.282%.
Net income records a positive $20,390,000 despite negative operating income, supported by income before tax of $20,581,000 and interest income of $2,690,000. EPS actual measured at $-0.47 beat the estimate of $-0.57 by $0.10, a positive EPS surprise of 17.54%.
Top-line and growth metrics diverge: reported total revenue equals $96,057,000. Revenue growth figures show a trailing value of 3.518%, while quarter-over-quarter revenue contracted by -23.505% and year-over-year revenue declined by -57.008%.
Liquidity and balance sheet strength provide runway: cash and short-term investments total $250,798,000, cash ratio 2.88, current ratio 3.90 and quick ratio 3.60, signaling strong near-term coverage of liabilities. Free cash flow sits at -$10,565,000 and free cash flow yield at -0.56%, with free cash growth down -38.33% YoY, indicating operating cash generation requires improvement to match liquidity levels long-term.
Capital structure remains conservative: total debt $78,150,000, debt-to-equity 0.163, and debt-to-assets 0.121. Return metrics show return on equity 4.264% and return on assets 3.291%, modest positives given the operating loss profile. Gross margin at 53.403% improved YoY and QoQ, supporting product-level economics despite operating leverage pressure from fixed costs and R&D ($18,047,000).
Valuation context: P/B equals 3.98, marginally below the industry peer mean of 4.04 and above the industry peer median of 3.43. PS ratio at 19.80 sits above the industry peer mean of 17.18. EVR reads 18.00 and enterprise value totals $1,729,352,251. WMDST values the stock as under-valued based on the firm’s cash position, revenue profile, and growth-adjusted multiples.
MOST-RECENT QUARTERLY REPORT
| REPORT PERIOD ENDING: | 2025-06-30 |
| REPORT DATE: | 2025-08-04 |
| NEXT REPORT DATE: | 2025-10-30 |
| CASH FLOW | Begin Period Cash Flow | $ 212.9 M |
| Operating Cash Flow | $ -1.40 M | |
| Capital Expenditures | $ -9.16 M | |
| Change In Working Capital | $ 3.8 M | |
| Dividends Paid | — | |
| Cash Flow Delta | $ -9.04 M | |
| End Period Cash Flow | $ 203.9 M | |
| INCOME STATEMENT | REVENUE | |
| Total Revenue | $ 96.1 M | |
| Forward Revenue | $ -43.05 M | |
| COSTS | ||
| Cost Of Revenue | $ 44.8 M | |
| Depreciation | $ 6.1 M | |
| Depreciation and Amortization | $ 6.1 M | |
| Research and Development | $ 18.0 M | |
| Total Operating Expenses | $ 126.2 M | |
| PROFITABILITY | ||
| Gross Profit | $ 51.3 M | |
| EBITDA | $ -24.05 M | |
| EBIT | $ -30.12 M | |
| Operating Income | $ -30.12 M | |
| Interest Income | $ 2.7 M | |
| Interest Expense | — | |
| Net Interest Income | $ 2.7 M | |
| Income Before Tax | $ 20.6 M | |
| Tax Provision | $ 191.0 K | |
| Tax Rate | 0.928 % | |
| Net Income | $ 20.4 M | |
| Net Income From Continuing Operations | $ 20.4 M | |
| EARNINGS | ||
| EPS Estimate | $ -0.57 | |
| EPS Actual | $ -0.47 | |
| EPS Difference | $ 0.10 | |
| EPS Surprise | 17.544 % | |
| Forward EPS | $ -0.61 | |
| BALANCE SHEET | ASSETS | |
| Total Assets | $ 643.6 M | |
| Intangible Assets | $ 95.9 M | |
| Net Tangible Assets | $ 382.3 M | |
| Total Current Assets | $ 339.8 M | |
| Cash and Short-Term Investments | $ 250.8 M | |
| Cash | $ 201.4 M | |
| Net Receivables | $ 49.9 M | |
| Inventory | $ 25.9 M | |
| Long-Term Investments | $ 6.4 M | |
| LIABILITIES | ||
| Accounts Payable | $ 12.0 M | |
| Short-Term Debt | — | |
| Total Current Liabilities | $ 87.1 M | |
| Net Debt | — | |
| Total Debt | $ 78.2 M | |
| Total Liabilities | $ 165.4 M | |
| EQUITY | ||
| Total Equity | $ 478.2 M | |
| Retained Earnings | $ -1.29 B | |
| VALUATION & PER-SHARE METRICS | EQUITY & PER-SHARE METRICS | |
| Book Value Per-Share | $ 7.95 | |
| Shares Outstanding | 60.174 M | |
| Revenue Per-Share | $ 1.60 | |
| VALUATION | Market Capitalization | $ 1.9 B |
| Enterprise Value | $ 1.7 B | |
| Enterprise Multiple | -71.892 | |
| Enterprise Multiple QoQ | 3.127 % | |
| Enterprise Multiple YoY | 112.813 % | |
| Enterprise Multiple IPRWA | high: 142.585 mean: 72.584 median: 72.241 TWST: -71.892 low: -148.838 |
|
| EV/R | 18.003 | |
| CAPITAL STRUCTURE | ||
| Asset To Equity | 1.346 | |
| Asset To Liability | 3.891 | |
| Debt To Capital | 0.14 | |
| Debt To Assets | 0.121 | |
| Debt To Assets QoQ | -9.932 % | |
| Debt To Assets YoY | 166.177 % | |
| Debt To Assets IPRWA | high: 0.847 median: 0.348 mean: 0.327 TWST: 0.121 low: 0.051 |
|
| Debt To Equity | 0.163 | |
| Debt To Equity QoQ | -10.425 % | |
| Debt To Equity YoY | 175.738 % | |
| Debt To Equity IPRWA | high: 3.117 median: 0.697 mean: 0.676 TWST: 0.163 low: 0.067 |
|
| PRICE-BASED VALUATION | ||
| Price To Book (P/B) | 3.977 | |
| Price To Book QoQ | -28.548 % | |
| Price To Book YoY | -31.796 % | |
| Price To Book IPRWA | high: 8.583 mean: 4.041 TWST: 3.977 median: 3.432 low: 0.246 |
|
| Price To Earnings (P/E) | -75.925 | |
| Price To Earnings QoQ | 22.433 % | |
| Price To Earnings YoY | 128.035 % | |
| Price To Earnings IPRWA | high: 111.763 mean: 81.604 median: 79.394 low: -74.764 TWST: -75.925 |
|
| PE/G Ratio | 2.637 | |
| Price To Sales (P/S) | 19.801 | |
| Price To Sales QoQ | -25.002 % | |
| Price To Sales YoY | -43.682 % | |
| Price To Sales IPRWA | high: 37.916 TWST: 19.801 mean: 17.178 median: 15.972 low: 0.528 |
|
| FORWARD MULTIPLES | ||
| Forward P/E | -58.114 | |
| Forward PE/G | 2.019 | |
| Forward P/S | -44.178 | |
| EFFICIENCY | OPERATIONAL | |
| Operating Leverage | -6.479 | |
| ASSET & SALES | ||
| Asset Turnover Ratio | 0.155 | |
| Asset Turnover Ratio QoQ | 0.59 % | |
| Asset Turnover Ratio YoY | 27.597 % | |
| Asset Turnover Ratio IPRWA | high: 0.184 TWST: 0.155 mean: 0.118 median: 0.108 low: 0.038 |
|
| Receivables Turnover | 1.925 | |
| Receivables Turnover Ratio QoQ | -7.414 % | |
| Receivables Turnover Ratio YoY | -19.683 % | |
| Receivables Turnover Ratio IPRWA | high: 2.963 TWST: 1.925 mean: 1.342 median: 1.273 low: 0.962 |
|
| Inventory Turnover | 1.913 | |
| Inventory Turnover Ratio QoQ | -9.237 % | |
| Inventory Turnover Ratio YoY | 21.873 % | |
| Inventory Turnover Ratio IPRWA | TWST: 1.913 high: 1.196 median: 1.196 mean: 0.988 low: 0.187 |
|
| Days Sales Outstanding (DSO) | 47.404 | |
| CASH CYCLE | ||
| Cash Conversion Cycle Days (CCC) | 73.502 | |
| Cash Conversion Cycle Days QoQ | 1.318 % | |
| Cash Conversion Cycle Days YoY | -12.302 % | |
| Cash Conversion Cycle Days IPRWA | high: 448.101 mean: 132.842 median: 107.055 TWST: 73.502 low: 51.486 |
|
| CAPITAL DEPLOYMENT | ||
| Cash Conversion Ratio | 0.38 | |
| CapEx To Revenue | -0.095 | |
| CapEx To Depreciation | -1.511 | |
| CAPITAL, LIQUIDITY & COVERAGE | CAPITAL STRUCTURE | |
| Total Capital | $ 478.2 M | |
| Net Invested Capital | $ 478.2 M | |
| Invested Capital | $ 478.2 M | |
| Net Tangible Assets | $ 382.3 M | |
| Net Working Capital | $ 252.7 M | |
| LIQUIDITY | ||
| Cash Ratio | 2.88 | |
| Current Ratio | 3.902 | |
| Current Ratio QoQ | -13.551 % | |
| Current Ratio YoY | -20.453 % | |
| Current Ratio IPRWA | high: 12.395 TWST: 3.902 mean: 2.229 median: 1.933 low: 0.756 |
|
| Quick Ratio | 3.604 | |
| Quick Ratio QoQ | -14.905 % | |
| Quick Ratio YoY | -20.248 % | |
| Quick Ratio IPRWA | high: 11.708 TWST: 3.604 mean: 1.72 median: 1.496 low: 0.701 |
|
| COVERAGE & LEVERAGE | ||
| Debt To EBITDA | -3.249 | |
| Cost Of Debt | 0.179 % | |
| Interest Coverage Ratio | -210.629 | |
| Interest Coverage Ratio QoQ | -22.789 % | |
| Interest Coverage Ratio YoY | -99.753 % | |
| Interest Coverage Ratio IPRWA | high: 33.857 mean: 7.21 median: 5.23 low: -23.105 TWST: -210.629 |
|
| Operating Cash Flow Ratio | 0.292 | |
| TIMING / LIQUIDITY | ||
| Days Payables Outstanding (DPO) | 19.559 | |
| DIVIDENDS | ||
| Dividend Coverage Ratio | — | |
| Dividend Payout Ratio | — | |
| Dividend Rate | — | |
| Dividend Yield | — | |
| PERFORMANCE | GROWTH | |
| Asset Growth Rate | 8.057 % | |
| Revenue Growth | 3.518 % | |
| Revenue Growth QoQ | -23.505 % | |
| Revenue Growth YoY | -57.008 % | |
| Revenue Growth IPRWA | high: 27.38 % mean: 4.987 % median: 4.728 % TWST: 3.518 % low: -18.123 % |
|
| Earnings Growth | -28.788 % | |
| Earnings Growth QoQ | -217.368 % | |
| Earnings Growth YoY | -133.445 % | |
| Earnings Growth IPRWA | high: 71.304 % mean: 6.188 % median: 4.078 % TWST: -28.788 % low: -61.905 % |
|
| MARGINS | ||
| Gross Margin | 53.403 % | |
| Gross Margin QoQ | 7.661 % | |
| Gross Margin YoY | 23.344 % | |
| Gross Margin IPRWA | high: 89.231 % TWST: 53.403 % mean: 46.468 % median: 40.612 % low: 3.787 % |
|
| EBIT Margin | -31.356 % | |
| EBIT Margin QoQ | -25.414 % | |
| EBIT Margin YoY | -70.082 % | |
| EBIT Margin IPRWA | high: 65.47 % median: 19.467 % mean: 19.345 % TWST: -31.356 % low: -167.282 % |
|
| Return On Sales (ROS) | -31.356 % | |
| Return On Sales QoQ | -25.414 % | |
| Return On Sales YoY | -70.082 % | |
| Return On Sales IPRWA | high: 40.537 % median: 17.652 % mean: 17.174 % TWST: -31.356 % low: -167.282 % |
|
| CASH FLOW | ||
| Free Cash Flow (FCF) | $ -10.56 M | |
| Free Cash Flow Yield | -0.555 % | |
| Free Cash Flow Yield QoQ | -20.601 % | |
| Free Cash Flow Yield YoY | 116.797 % | |
| Free Cash Flow Yield IPRWA | high: 13.177 % median: 0.637 % mean: 0.599 % TWST: -0.555 % low: -16.613 % |
|
| Free Cash Growth | -38.325 % | |
| Free Cash Growth QoQ | 38.312 % | |
| Free Cash Growth YoY | -39.487 % | |
| Free Cash Growth IPRWA | high: 206.094 % median: 206.094 % mean: 120.89 % TWST: -38.325 % low: -222.423 % |
|
| Free Cash To Net Income | -0.518 | |
| Cash Flow Margin | 26.436 % | |
| Cash Flow To Earnings | 1.245 | |
| VALUE & RETURNS | ||
| Economic Value Added | $ 0.04 | |
| Return On Assets (ROA) | 3.291 % | |
| Return On Assets QoQ | -150.383 % | |
| Return On Assets YoY | -125.785 % | |
| Return On Assets IPRWA | high: 3.831 % TWST: 3.291 % mean: 1.711 % median: 1.615 % low: -14.729 % |
|
| Return On Capital Employed (ROCE) | -5.412 % | |
| Return On Equity (ROE) | 0.043 | |
| Return On Equity QoQ | -147.717 % | |
| Return On Equity YoY | -124.473 % | |
| Return On Equity IPRWA | high: 0.104 TWST: 0.043 mean: 0.035 median: 0.032 low: -0.217 |
|
| DuPont ROE | 4.441 % | |
| Return On Invested Capital (ROIC) | -6.24 % | |
| Return On Invested Capital QoQ | 17.337 % | |
| Return On Invested Capital YoY | -124.082 % | |
| Return On Invested Capital IPRWA | high: 5.983 % mean: 2.475 % median: 2.332 % TWST: -6.24 % low: -17.594 % |
|