Recent News
Investor’s Business Daily reported an RS Rating upgrade for AnaptysBio in August 2025, noting improving price momentum and highlighting a recent surge in sales; a follow-up IBD item recorded the RS Rating crossing the 80 threshold the same period, citing the company’s strong sales increase alongside unchanged EPS growth.
Technical Analysis
ADX/DI+/DI-: ADX at 21.64 indicates an emerging trend in strength; DIpositive shows a dip & reversal while DInegative shows a peak & reversal, which together imply directional bullish pressure building against prior negative bias.
MACD: MACD reads -0.19 with a dip & reversal and a signal at -0.28; the MACD currently sits above its signal line, constituting a bullish momentum shift that supports short-term upside potential.
MRO (Momentum/Regression Oscillator): MRO registers -20.49 with a dip & reversal, indicating price sits below modeled target and therefore carries potential to increase toward that target.
RSI and Momentum: RSI at 47.84 with a dip & reversal shows recovery from a short-term pullback while remaining near neutral, suggesting room for further momentum without immediate overbought risk.
Price Versus Moving Averages & Bands: Current close at $22.14 trades above the 200-day average of $19.84 and above the 20-day average of $21.53 but slightly below the 50-day average of $22.39; price sits just under the 1x Bollinger upper band ($22.90), indicating proximity to recent resistance and a compact volatility environment.
Ichimoku & Support: Ichimoku Senkou A $23.57 and Senkou B $23.77 place the cloud above current price, creating a defined resistance zone near those levels while the SuperTrend lower support sits at $19.14.
Fundamental Analysis
Profitability: EBIT at -$18,985,000 yields an EBIT margin of -85.28%, a QoQ improvement of +11.58% but a YoY decline of -73.79%; the EBIT margin sits below the industry peer mean of -75.17% and below the industry peer median of 23.76% when expressed in percentage terms.
Revenue & Growth: Total revenue reached $22,263,000 with revenue growth quarter-over-quarter at -44.27% and YoY at -137.55%; these figures indicate near-term top-line contraction versus the prior period despite product and pipeline momentum reported in recent headlines.
Earnings Per Share: GAAP EPS stood at -$1.34 versus an estimate of -$1.58, producing an EPS surprise of +15.19% on the release and showing a smaller-than-expected loss on the period.
Cash, Liquidity & Capital Structure: Cash and short-term investments total $265,710,000 with a cash balance of $44,298,000 and a cash ratio of 7.48; current ratio equals 8.22, signaling abundant near-term liquidity. Total debt sits at $15,096,000, and debt-to-assets measures 4.50%, below the industry peer mean of 19.48%.
Cash Flow & R&D: Operating cash flow and free cash flow both approximate -$40.2M and -$40.3M respectively; research and development expense reached $37,824,000, reflecting continued pipeline investment that underpins long-term value creation despite the negative cash-flow run.
Valuation Metrics: EV/Revenue and enterprise multiple readings include an EVR of 16.54 and an enterprise multiple of -20.03; price-to-sales stands at 27.80 while P/B reads -13.83. WMDST values the stock as under-valued based on internal valuation work provided with these metrics.
MOST-RECENT QUARTERLY REPORT
| REPORT PERIOD ENDING: | 2025-06-30 |
| REPORT DATE: | 2025-08-06 |
| NEXT REPORT DATE: | 2025-11-03 |
| CASH FLOW | Begin Period Cash Flow | $ 98.6 M |
| Operating Cash Flow | $ -40.24 M | |
| Capital Expenditures | $ -39.00 K | |
| Change In Working Capital | $ -29.46 M | |
| Dividends Paid | — | |
| Cash Flow Delta | $ -54.34 M | |
| End Period Cash Flow | $ 44.3 M | |
| INCOME STATEMENT | REVENUE | |
| Total Revenue | $ 22.3 M | |
| Forward Revenue | $ 6.5 M | |
| COSTS | ||
| Cost Of Revenue | — | |
| Depreciation | $ 601.0 K | |
| Depreciation and Amortization | $ 601.0 K | |
| Research and Development | $ 37.8 M | |
| Total Operating Expenses | $ 48.4 M | |
| PROFITABILITY | ||
| Gross Profit | — | |
| EBITDA | $ -18.38 M | |
| EBIT | $ -18.98 M | |
| Operating Income | $ -26.17 M | |
| Interest Income | $ 3.7 M | |
| Interest Expense | $ 19.6 M | |
| Net Interest Income | $ -15.95 M | |
| Income Before Tax | $ -38.59 M | |
| Tax Provision | $ 39.0 K | |
| Tax Rate | 21.0 % | |
| Net Income | $ -38.63 M | |
| Net Income From Continuing Operations | $ -38.63 M | |
| EARNINGS | ||
| EPS Estimate | $ -1.58 | |
| EPS Actual | $ -1.34 | |
| EPS Difference | $ 0.24 | |
| EPS Surprise | 15.19 % | |
| Forward EPS | $ -1.60 | |
| BALANCE SHEET | ASSETS | |
| Total Assets | $ 335.2 M | |
| Intangible Assets | — | |
| Net Tangible Assets | $ -44.73 M | |
| Total Current Assets | $ 291.9 M | |
| Cash and Short-Term Investments | $ 265.7 M | |
| Cash | $ 44.3 M | |
| Net Receivables | $ 21.4 M | |
| Inventory | — | |
| Long-Term Investments | $ 256.0 K | |
| LIABILITIES | ||
| Accounts Payable | $ 3.3 M | |
| Short-Term Debt | — | |
| Total Current Liabilities | $ 35.5 M | |
| Net Debt | — | |
| Total Debt | $ 15.1 M | |
| Total Liabilities | $ 380.0 M | |
| EQUITY | ||
| Total Equity | $ -44.73 M | |
| Retained Earnings | $ -837.29 M | |
| VALUATION & PER-SHARE METRICS | EQUITY & PER-SHARE METRICS | |
| Book Value Per-Share | $ -1.60 | |
| Shares Outstanding | 27.973 M | |
| Revenue Per-Share | $ 0.80 | |
| VALUATION | Market Capitalization | $ 618.8 M |
| Enterprise Value | $ 368.2 M | |
| Enterprise Multiple | -20.029 | |
| Enterprise Multiple QoQ | 66.355 % | |
| Enterprise Multiple YoY | 62.305 % | |
| Enterprise Multiple IPRWA | high: 47.216 median: 14.143 mean: 5.444 ANAB: -20.029 low: -68.907 |
|
| EV/R | 16.539 | |
| CAPITAL STRUCTURE | ||
| Asset To Equity | -7.494 | |
| Asset To Liability | 0.882 | |
| Debt To Capital | -0.509 | |
| Debt To Assets | 0.045 | |
| Debt To Assets QoQ | 22.033 % | |
| Debt To Assets YoY | 419.977 % | |
| Debt To Assets IPRWA | high: 0.995 mean: 0.195 median: 0.062 ANAB: 0.045 low: 0.0 |
|
| Debt To Equity | -0.337 | |
| Debt To Equity QoQ | -173.714 % | |
| Debt To Equity YoY | -190.105 % | |
| Debt To Equity IPRWA | high: 1.577 mean: 0.256 median: 0.059 ANAB: -0.337 low: -1.039 |
|
| PRICE-BASED VALUATION | ||
| Price To Book (P/B) | -13.834 | |
| Price To Book QoQ | -182.194 % | |
| Price To Book YoY | -117.515 % | |
| Price To Book IPRWA | high: 16.592 median: 6.295 mean: 5.278 low: -9.599 ANAB: -13.834 |
|
| Price To Earnings (P/E) | -17.61 | |
| Price To Earnings QoQ | 19.623 % | |
| Price To Earnings YoY | 5.874 % | |
| Price To Earnings IPRWA | high: 44.732 mean: -11.172 ANAB: -17.61 median: -19.271 low: -73.374 |
|
| PE/G Ratio | -3.756 | |
| Price To Sales (P/S) | 27.796 | |
| Price To Sales QoQ | 34.811 % | |
| Price To Sales YoY | -60.918 % | |
| Price To Sales IPRWA | high: 517.227 mean: 56.272 ANAB: 27.796 median: 19.711 low: 0.25 |
|
| FORWARD MULTIPLES | ||
| Forward P/E | -13.244 | |
| Forward PE/G | -2.825 | |
| Forward P/S | 95.815 | |
| EFFICIENCY | OPERATIONAL | |
| Operating Leverage | 0.532 | |
| ASSET & SALES | ||
| Asset Turnover Ratio | 0.059 | |
| Asset Turnover Ratio QoQ | -4.094 % | |
| Asset Turnover Ratio YoY | 123.319 % | |
| Asset Turnover Ratio IPRWA | high: 0.388 mean: 0.115 median: 0.113 ANAB: 0.059 low: -0.001 |
|
| Receivables Turnover | 1.133 | |
| Receivables Turnover Ratio QoQ | 19.63 % | |
| Receivables Turnover Ratio YoY | -16.893 % | |
| Receivables Turnover Ratio IPRWA | high: 7.487 median: 1.422 mean: 1.409 ANAB: 1.133 low: 0.012 |
|
| Inventory Turnover | — | |
| Inventory Turnover Ratio QoQ | — | |
| Inventory Turnover Ratio YoY | — | |
| Inventory Turnover Ratio IPRWA | — | |
| Days Sales Outstanding (DSO) | 80.544 | |
| CASH CYCLE | ||
| Cash Conversion Cycle Days (CCC) | — | |
| Cash Conversion Cycle Days QoQ | — | |
| Cash Conversion Cycle Days YoY | — | |
| Cash Conversion Cycle Days IPRWA | — | |
| CAPITAL DEPLOYMENT | ||
| Cash Conversion Ratio | 0.087 | |
| CapEx To Revenue | -0.002 | |
| CapEx To Depreciation | -0.065 | |
| CAPITAL, LIQUIDITY & COVERAGE | CAPITAL STRUCTURE | |
| Total Capital | $ -44.73 M | |
| Net Invested Capital | $ -44.73 M | |
| Invested Capital | $ -44.73 M | |
| Net Tangible Assets | $ -44.73 M | |
| Net Working Capital | $ 256.4 M | |
| LIQUIDITY | ||
| Cash Ratio | 7.479 | |
| Current Ratio | 8.216 | |
| Current Ratio QoQ | -0.354 % | |
| Current Ratio YoY | -9.593 % | |
| Current Ratio IPRWA | high: 25.128 ANAB: 8.216 mean: 3.946 median: 2.52 low: 0.021 |
|
| Quick Ratio | — | |
| Quick Ratio QoQ | — | |
| Quick Ratio YoY | — | |
| Quick Ratio IPRWA | — | |
| COVERAGE & LEVERAGE | ||
| Debt To EBITDA | -0.821 | |
| Cost Of Debt | 100.999 % | |
| Interest Coverage Ratio | -0.968 | |
| Interest Coverage Ratio QoQ | -17.598 % | |
| Interest Coverage Ratio YoY | -70.289 % | |
| Interest Coverage Ratio IPRWA | high: 940.414 mean: 45.45 median: 2.742 ANAB: -0.968 low: -1465.352 |
|
| Operating Cash Flow Ratio | -1.249 | |
| TIMING / LIQUIDITY | ||
| Days Payables Outstanding (DPO) | — | |
| DIVIDENDS | ||
| Dividend Coverage Ratio | — | |
| Dividend Payout Ratio | — | |
| Dividend Rate | — | |
| Dividend Yield | — | |
| PERFORMANCE | GROWTH | |
| Asset Growth Rate | -20.567 % | |
| Revenue Growth | -19.834 % | |
| Revenue Growth QoQ | -44.265 % | |
| Revenue Growth YoY | -137.549 % | |
| Revenue Growth IPRWA | high: 303.4 % mean: 20.885 % median: 12.272 % ANAB: -19.834 % low: -259.856 % |
|
| Earnings Growth | 4.688 % | |
| Earnings Growth QoQ | -93.973 % | |
| Earnings Growth YoY | 9.841 % | |
| Earnings Growth IPRWA | high: 155.0 % median: 11.33 % ANAB: 4.688 % mean: 2.361 % low: -181.25 % |
|
| MARGINS | ||
| Gross Margin | — | |
| Gross Margin QoQ | — | |
| Gross Margin YoY | — | |
| Gross Margin IPRWA | — | |
| EBIT Margin | -85.276 % | |
| EBIT Margin QoQ | 11.581 % | |
| EBIT Margin YoY | -73.792 % | |
| EBIT Margin IPRWA | high: 338.783 % median: 23.755 % mean: -75.171 % ANAB: -85.276 % low: -5123.44 % |
|
| Return On Sales (ROS) | -117.549 % | |
| Return On Sales QoQ | 53.81 % | |
| Return On Sales YoY | -63.874 % | |
| Return On Sales IPRWA | high: 89.247 % median: 28.85 % mean: -78.972 % ANAB: -117.549 % low: -5698.0 % |
|
| CASH FLOW | ||
| Free Cash Flow (FCF) | $ -40.28 M | |
| Free Cash Flow Yield | -6.51 % | |
| Free Cash Flow Yield QoQ | 247.2 % | |
| Free Cash Flow Yield YoY | 137.852 % | |
| Free Cash Flow Yield IPRWA | high: 36.371 % median: 0.516 % mean: -0.334 % ANAB: -6.51 % low: -74.318 % |
|
| Free Cash Growth | 275.249 % | |
| Free Cash Growth QoQ | -427.826 % | |
| Free Cash Growth YoY | -744.355 % | |
| Free Cash Growth IPRWA | ANAB: 275.249 % high: 157.51 % median: 13.256 % mean: 3.868 % low: -183.577 % |
|
| Free Cash To Net Income | 1.043 | |
| Cash Flow Margin | -199.241 % | |
| Cash Flow To Earnings | 1.148 | |
| VALUE & RETURNS | ||
| Economic Value Added | $ 0.06 | |
| Return On Assets (ROA) | -10.202 % | |
| Return On Assets QoQ | 17.494 % | |
| Return On Assets YoY | -8.911 % | |
| Return On Assets IPRWA | high: 36.544 % median: 1.616 % mean: -1.369 % ANAB: -10.202 % low: -68.545 % |
|
| Return On Capital Employed (ROCE) | -6.334 % | |
| Return On Equity (ROE) | 0.864 | |
| Return On Equity QoQ | -174.702 % | |
| Return On Equity YoY | -118.284 % | |
| Return On Equity IPRWA | high: 1.117 ANAB: 0.864 median: 0.04 mean: 0.008 low: -1.572 |
|
| DuPont ROE | 721.304 % | |
| Return On Invested Capital (ROIC) | 33.528 % | |
| Return On Invested Capital QoQ | -189.573 % | |
| Return On Invested Capital YoY | 312.652 % | |
| Return On Invested Capital IPRWA | high: 53.785 % ANAB: 33.528 % median: 3.175 % mean: 1.466 % low: -71.959 % |
|