Immunocore Holdings Plc (NASDAQ:IMCR) Secures Phase‑3 Enrollment, Catalysts Point To Near‑Term Upside

Immunocore enters a catalyst-rich stretch after completing key trial enrollment and reporting mid‑year commercial traction; liquidity and pipeline timing support a constructive near-term view. Upcoming trial readouts represent primary directional drivers.

Recent News

On August 6, 2026 the company published second‑quarter results and a business update reporting KIMMTRAK net product revenue of $115.9 million and disclosing ongoing Phase 1/2 and Phase 3 development milestones. On September 14, 2026 the company announced it achieved target enrollment of 540 patients in its registrational Phase 3 TEBE‑AM trial of KIMMTRAK in previously treated advanced melanoma.

Technical Analysis

ADX at 25.09 indicates a strong trend in place; directional indicators show DI‑ rising to 24.62 while DI+ falls to 18.44, a configuration that signals prevailing downside directional pressure and reinforces the near‑term bearish bias.

MACD sits negative at –0.67 and trends downward, remaining below its signal line (–0.17); momentum structure therefore favors further downside until momentum stabilizes or a MACD cross reverses that trajectory.

Price trades below short‑ and medium‑term averages (12‑day EMA $33.22, 20‑day $34.02, 50‑day $34.60 and 200‑day $32.48), a pattern consistent with short‑term weakness relative to the current valuation and supporting the immediate bearish price bias.

MRO at –2.83 registers negative, indicating the market price sits below the model target and implying some upside potential toward fair value if sentiment shifts or catalysts land favorably.

RSI at 50.21 and trending lower shows neutral momentum slipping; the indicator neither signals oversold relief nor strong buying pressure, so price may remain range‑bound absent a catalyst.

Fundamental Analysis

Profitability: EBIT stands at $2,001,000 and EBIT margin equals 1.73%. QoQ change in EBIT margin registers –88.72% and YoY change –123.55%, reflecting compression in recent operating leverage. EPS actual registered –$0.02 versus an estimate of $0.02, an EPS surprise of –200% driven by the negative result versus consensus.

Revenue and margins: Total revenue reached $115,927,000 with YoY revenue growth of 99.38% and QoQ growth of 311.92%. Gross margin remains elevated at 99.06%, well above the industry peer mean of 78.12%, supporting high incremental profitability on product sales even as operating margins remain negative at –2.58%.

Liquidity and balance sheet: Cash and short‑term investments total $880,211,000 and the current ratio equals 4.47x (quick ratio 4.44x), both above the industry peer mean for current ratio (3.00x), indicating ample near‑term liquidity to fund operations and pipeline progress. Total debt equals $434,959,000 with debt‑to‑equity at 1.04x and interest coverage at 0.80x, the latter showing operating earnings do not fully cover interest expense at present.

Efficiency and cash flow: Asset turnover measures 0.106, slightly below the industry peer mean of 0.1185, while cash conversion cycle sits at –4,181 days (negative), a structural working‑capital profile driven by timing in payables/receivables. Free cash flow totaled $15,142,000 with a free cash flow yield of 0.93%.

Valuation and WMDST view: Price multiples show P/B at 3.87x and PS at 14.01x while reported PE and forward PE are negative given current losses; enterprise value measures deliver an EVR of 10.16. The current valuation as determined by WMDST classifies the stock as under‑valued, with near‑term re‑rating contingent on clinical readouts and sustained commercial revenues.

MOST-RECENT QUARTERLY REPORT
REPORT PERIOD ENDING: 2026-06-30
REPORT DATE: 2026-08-06
NEXT REPORT DATE: 2026-11-05
CASH FLOW  Begin Period Cash Flow 452.7 M
 Operating Cash Flow 15.9 M
 Capital Expenditures -786.00 K
 Change In Working Capital 7.4 M
 Dividends Paid
 Cash Flow Delta 32.2 M
 End Period Cash Flow 484.9 M
 
INCOME STATEMENT REVENUE
 Total Revenue 115.9 M
 Forward Revenue 346.7 M
COSTS
 Cost Of Revenue 1.1 M
 Depreciation 1.0 M
 Depreciation and Amortization 1.0 M
 Research and Development 73.9 M
 Total Operating Expenses 118.9 M
PROFITABILITY
 Gross Profit 114.8 M
 EBITDA 3.0 M
 EBIT 2.0 M
 Operating Income -3.00 M
 Interest Income 3.6 M
 Interest Expense 2.5 M
 Net Interest Income 520.0 K
 Income Before Tax -514.00 K
 Tax Provision 294.0 K
 Tax Rate 40.0 %
 Net Income -808.00 K
 Net Income From Continuing Operations -808.00 K
EARNINGS
 EPS Estimate 0.02
 EPS Actual -0.02
 EPS Difference -0.04
 EPS Surprise -200.0 %
 Forward EPS -0.19
 
BALANCE SHEET ASSETS
 Total Assets 1.1 B
 Intangible Assets
 Net Tangible Assets 419.8 M
 Total Current Assets 1.1 B
 Cash and Short-Term Investments 880.2 M
 Cash 484.9 M
 Net Receivables 95.3 M
 Inventory 7.8 M
 Long-Term Investments 18.5 M
LIABILITIES
 Accounts Payable 26.3 M
 Short-Term Debt
 Total Current Liabilities 235.2 M
 Net Debt
 Total Debt 435.0 M
 Total Liabilities 699.6 M
EQUITY
 Total Equity 419.8 M
 Retained Earnings -819.11 M
VALUATION & PER-SHARE METRICS EQUITY & PER-SHARE METRICS
 Book Value Per-Share 8.25
 Shares Outstanding 51.480 M
 Revenue Per-Share 2.28
VALUATION
 Market Capitalization 1.6 B
 Enterprise Value 1.2 B
 Enterprise Multiple 389.293
Enterprise Multiple QoQ 474.895 %
Enterprise Multiple YoY -305.865 %
Enterprise Multiple IPRWA IMCR: 389.293
high: 85.287
mean: 10.203
median: -1.048
low: -121.71
 EV/R 10.165
CAPITAL STRUCTURE
 Asset To Equity 2.667
 Asset To Liability 1.6
 Debt To Capital 0.509
 Debt To Assets 0.389
Debt To Assets QoQ -4.385 %
Debt To Assets YoY -3.641 %
Debt To Assets IPRWA high: 1.088
IMCR: 0.389
mean: 0.143
median: 0.018
low: 0.0
 Debt To Equity 1.036
Debt To Equity QoQ -6.379 %
Debt To Equity YoY -7.779 %
Debt To Equity IPRWA high: 1.719
IMCR: 1.036
mean: 0.135
median: 0.037
low: -1.043
PRICE-BASED VALUATION
 Price To Book (P/B) 3.868
Price To Book QoQ -3.555 %
Price To Book YoY -9.29 %
Price To Book IPRWA high: 19.973
mean: 8.201
median: 6.334
IMCR: 3.868
low: -9.25
 Price To Earnings (P/E) -1596.012
Price To Earnings QoQ -1384.712 %
Price To Earnings YoY 860.89 %
Price To Earnings IPRWA high: 76.582
mean: -2.6
median: -19.402
low: -123.087
IMCR: -1596.012
 PE/G Ratio 14.778
 Price To Sales (P/S) 14.006
Price To Sales QoQ -5.361 %
Price To Sales YoY -17.166 %
Price To Sales IPRWA high: 879.061
mean: 55.98
median: 28.439
IMCR: 14.006
low: 0.181
FORWARD MULTIPLES
Forward P/E -172.923
Forward PE/G 1.601
Forward P/S 5.176
EFFICIENCY OPERATIONAL
 Operating Leverage -10.119
ASSET & SALES
 Asset Turnover Ratio 0.106
Asset Turnover Ratio QoQ 6.086 %
Asset Turnover Ratio YoY 13.96 %
Asset Turnover Ratio IPRWA high: 0.427
mean: 0.118
median: 0.107
IMCR: 0.106
low: 0.0
 Receivables Turnover 1.314
Receivables Turnover Ratio QoQ -4.495 %
Receivables Turnover Ratio YoY -10.885 %
Receivables Turnover Ratio IPRWA high: 5.69
median: 1.538
mean: 1.453
IMCR: 1.314
low: 0.004
 Inventory Turnover 0.136
Inventory Turnover Ratio QoQ 134.289 %
Inventory Turnover Ratio YoY -20.058 %
Inventory Turnover Ratio IPRWA high: 3.295
mean: 0.6
median: 0.453
IMCR: 0.136
low: 0.004
 Days Sales Outstanding (DSO) 69.432
CASH CYCLE
 Cash Conversion Cycle Days (CCC) -4181.052
Cash Conversion Cycle Days QoQ 595.841 %
Cash Conversion Cycle Days YoY 92.43 %
Cash Conversion Cycle Days IPRWA high: 1415.294
median: 197.717
mean: 190.308
low: -1418.404
IMCR: -4181.052
CAPITAL DEPLOYMENT
 Cash Conversion Ratio 0.142
 CapEx To Revenue -0.007
 CapEx To Depreciation -0.766
 
CAPITAL, LIQUIDITY & COVERAGE CAPITAL STRUCTURE
 Total Capital 814.0 M
 Net Invested Capital 814.0 M
 Invested Capital 814.0 M
 Net Tangible Assets 419.8 M
 Net Working Capital 815.8 M
LIQUIDITY
 Cash Ratio 3.742
 Current Ratio 4.469
Current Ratio QoQ 6.894 %
Current Ratio YoY -24.171 %
Current Ratio IPRWA high: 31.351
IMCR: 4.469
mean: 3.002
median: 1.265
low: 0.026
 Quick Ratio 4.436
Quick Ratio QoQ 6.981 %
Quick Ratio YoY -24.321 %
Quick Ratio IPRWA high: 13.027
IMCR: 4.436
mean: 2.664
median: 2.323
low: 0.047
COVERAGE & LEVERAGE
 Debt To EBITDA 143.693
 Cost Of Debt 0.347 %
 Interest Coverage Ratio 0.796
Interest Coverage Ratio QoQ -85.129 %
Interest Coverage Ratio YoY -127.873 %
Interest Coverage Ratio IPRWA high: 672.667
IMCR: 0.796
mean: -15.973
median: -59.087
low: -1866.8
 Operating Cash Flow Ratio -0.074
TIMING / LIQUIDITY
 Days Payables Outstanding (DPO) 5937.137
DIVIDENDS
 Dividend Coverage Ratio
 Dividend Payout Ratio
 Dividend Rate
 Dividend Yield
PERFORMANCE GROWTH
 Asset Growth Rate 4.414 %
 Revenue Growth 8.671 %
Revenue Growth QoQ 311.924 %
Revenue Growth YoY 99.379 %
Revenue Growth IPRWA high: 330.841 %
mean: 15.687 %
median: 14.284 %
IMCR: 8.671 %
low: -242.388 %
 Earnings Growth -108.0 %
Earnings Growth QoQ -23.765 %
Earnings Growth YoY -64.0 %
Earnings Growth IPRWA high: 168.75 %
median: 10.526 %
mean: 10.193 %
IMCR: -108.0 %
low: -155.294 %
MARGINS
 Gross Margin 99.061 %
Gross Margin QoQ -0.534 %
Gross Margin YoY 0.124 %
Gross Margin IPRWA high: 100.0 %
IMCR: 99.061 %
median: 79.764 %
mean: 78.122 %
low: -70.566 %
 EBIT Margin 1.726 %
EBIT Margin QoQ -88.72 %
EBIT Margin YoY -123.553 %
EBIT Margin IPRWA high: 212.221 %
median: 25.974 %
IMCR: 1.726 %
mean: -101.04 %
low: -4214.74 %
 Return On Sales (ROS) -2.584 %
Return On Sales QoQ -137.866 %
Return On Sales YoY -82.982 %
Return On Sales IPRWA high: 78.757 %
median: 32.539 %
IMCR: -2.584 %
mean: -82.78 %
low: -3837.989 %
CASH FLOW
 Free Cash Flow (FCF) 15.1 M
 Free Cash Flow Yield 0.933 %
Free Cash Flow Yield QoQ -194.721 %
Free Cash Flow Yield YoY -39.533 %
Free Cash Flow Yield IPRWA high: 29.465 %
IMCR: 0.933 %
median: 0.852 %
mean: 0.259 %
low: -49.548 %
 Free Cash Growth -197.339 %
Free Cash Growth QoQ 250.993 %
Free Cash Growth YoY -101.064 %
Free Cash Growth IPRWA high: 175.34 %
median: 24.96 %
mean: 20.987 %
IMCR: -197.339 %
low: -197.399 %
 Free Cash To Net Income -18.74
 Cash Flow Margin -15.044 %
 Cash Flow To Earnings 21.584
VALUE & RETURNS
 Economic Value Added 0.03
 Return On Assets (ROA) -0.074 %
Return On Assets QoQ -106.101 %
Return On Assets YoY -92.418 %
Return On Assets IPRWA high: 34.781 %
IMCR: -0.074 %
mean: -8.88 %
median: -13.258 %
low: -66.894 %
 Return On Capital Employed (ROCE) 0.226 %
 Return On Equity (ROE) -0.002
Return On Equity QoQ -105.827 %
Return On Equity YoY -92.757 %
Return On Equity IPRWA high: 0.746
IMCR: -0.002
mean: -0.177
median: -0.259
low: -1.213
 DuPont ROE -0.199 %
 Return On Invested Capital (ROIC) 0.147 %
Return On Invested Capital QoQ -92.744 %
Return On Invested Capital YoY -120.22 %
Return On Invested Capital IPRWA high: 37.515 %
median: 3.876 %
IMCR: 0.147 %
mean: -0.774 %
low: -47.859 %

Six-Week Outlook

Expect a volatility‑sensitive range as technical momentum currently favors downside but model mismatch (negative MRO) leaves room for rallies on positive catalyst delivery. Trial enrollment completion and Q2 revenue beats place data and commercial cadence at center stage; absent fresh positive data, price should trade within a roughly $31–$36 band, while a confirmed positive readout or materially stronger guidance would increase upside capture toward analyst target clustering.

About Immunocore Holdings plc

Immunocore Holdings plc (NASDAQ:IMCR) develops innovative immunotherapies aimed at treating cancer, infectious diseases, and autoimmune conditions. Based in Abingdon, UK, the company advances its proprietary ImmTAC technology platform to harness the body’s immune system in combating diseases. Immunocore’s leading product, KIMMTRAK, targets unresectable or metastatic uveal melanoma, offering a novel treatment option for patients. The company’s pipeline includes tebentafusp, currently progressing through Phase 2/3 trials for advanced cutaneous melanoma. Additionally, Immunocore evaluates IMC-F106C in Phase 3 trials for first-line advanced cutaneous melanoma and in Phase 1/2 trials for a range of tumors, such as ovarian and lung cancers. The company also explores therapies for colorectal, gastrointestinal, and viral infections with candidates like IMC-R117C and IMC-M113V. Committed to addressing unmet medical needs, Immunocore conducts preclinical trials targeting solid tumor cancers and type 1 diabetes. Founded in 1999, Immunocore leverages its expertise to deliver transformative therapies, aiming to improve patient outcomes across the globe.



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